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2''-O-Galloylhyperin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2''-O-Galloylhyperin
Price: $118 / 20mg
CAS No.: 53209-27-1
Catalog No.: CFN99728
Molecular Formula: C28H24O16
Molecular Weight: 616.48 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The herbs of Hypericum perforatum L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $41.1 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 2''-O-Galloylhyperin has effects on arrhythmias in an isolated tissue model of hypoxia and reperfusion.
In vitro:
Chin. Pharm. Bull., 2002, 18(3).
Effects of 2''-O-Galloylhyperin on arrhythmias in an isolated tissue model of hypoxia and reperfusion[Reference: WebLink]
Effects of 2''-O-Galloylhyperin on arrhythmias in an isolated tissue model of hypoxia and reperfusion
2''-O-Galloylhyperin Description
Source: The herbs of Hypericum perforatum L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6221 mL 8.1106 mL 16.2211 mL 32.4423 mL 40.5528 mL
5 mM 0.3244 mL 1.6221 mL 3.2442 mL 6.4885 mL 8.1106 mL
10 mM 0.1622 mL 0.8111 mL 1.6221 mL 3.2442 mL 4.0553 mL
50 mM 0.0324 mL 0.1622 mL 0.3244 mL 0.6488 mL 0.8111 mL
100 mM 0.0162 mL 0.0811 mL 0.1622 mL 0.3244 mL 0.4055 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Biodivers. 2007 Dec;4(12):2932-7.
Tetralones and flavonoids from Pyrola calliantha.[Pubmed: 18081103]

METHODS AND RESULTS:
Two new tetralones, pyrolones A (1) and B (2), and a new flavonol glycoside, 2''-O-(4-hydroxybenzoyl)hyperin (3), were isolated from Pyrola calliantha (whole plant), together with six structurally related compounds, including 2''-O-Galloylhyperin (4), hyperin (5), formononetin (6), quercetin 3-O-alpha-L-arabinopyranoside (7), quercetin 3-O-alpha-L-arabinofuranoside (8), and kaempferol 3-O-beta-D-galactopyranoside (9).
CONCLUSIONS:
The structures and absolute configurations of the new compounds were elucidated on the basis of spectroscopic (UV, ORD, CD, NMR) and mass-spectrometric (HR-ESI-MS) analyses.
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