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3,27-Dihydroxy-20(29)-lupen-28-oic acid methyl ester
3,27-Dihydroxy-20(29)-lupen-28-oic acid methyl ester
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 3,27-Dihydroxy-20(29)-lupen-28-oic acid methyl ester
Price:
CAS No.: 263844-79-7
Catalog No.: CFN98305
Molecular Formula: C31H50O4
Molecular Weight: 486.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Peganum harmala
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Biological Activity
Description: 3α, 27-Dihydroxylupen-20(29)-en-28-oic acid methyl ester is a potent topoisomerase II inhibitor.
Targets: Topoisomerase II
3,27-Dihydroxy-20(29)-lupen-28-oic acid methyl ester Description
Source: The herbs of Peganum harmala
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0547 mL 10.2733 mL 20.5465 mL 41.0931 mL 51.3663 mL
5 mM 0.4109 mL 2.0547 mL 4.1093 mL 8.2186 mL 10.2733 mL
10 mM 0.2055 mL 1.0273 mL 2.0547 mL 4.1093 mL 5.1366 mL
50 mM 0.0411 mL 0.2055 mL 0.4109 mL 0.8219 mL 1.0273 mL
100 mM 0.0205 mL 0.1027 mL 0.2055 mL 0.4109 mL 0.5137 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron Letters, 2004, 45(16):3261-3263.
Determination of the absolute stereochemistry of lupane triterpenoids by fucofuranoside method and ORD spectrum[Reference: WebLink]

METHODS AND RESULTS:
The absolute configurations of the secondary alcohols at C-3 position in betulinic acid and 3-epibetulinic acid have been unambiguously determined as S- and R-configurations, respectively, based on the fucofuranoside method.
CONCLUSIONS:
The absolute stereochemistry of 3α, 27-dihydroxylupen-20(29)-en-28-oic acid methyl ester (3,27-Dihydroxy-20(29)-lupen-28-oic acid methyl ester ), a potent topoisomerase II inhibitor, was determined to be 3R, 5R, 8R, 9R, 10R, 13R, 14S, 17S, 18R, and 19R by NMR and ORD spectroscopic studies.
Malvidin-3-O-glucoside chloride

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Price: $168/10mg
Flavone

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CAS No: 525-82-6
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Hypericin

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Isoliensinine

Catalog No: CFN99574
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Price: $80/20mg
Coumestrol

Catalog No: CFN96040
CAS No: 479-13-0
Price: $178/10mg
Swertiajaponin

Catalog No: CFN90652
CAS No: 6980-25-2
Price: $218/10mg
Jatrorrhizine

Catalog No: CFN98493
CAS No: 3621-38-3
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Vomifoliol

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CAS No: 23526-45-6
Price: $ /
Cucurbitacin B

Catalog No: CFN99129
CAS No: 6199-67-3
Price: $70/20mg
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