3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan | CAS:873867-94-8

3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

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Product Name	3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan
Price:
CAS No.:	873867-94-8
Catalog No.:	CFN96935
Molecular Formula:	C₂₂H₂₄O₇
Molecular Weight:	400.42 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Powder
Source:	The roots of Artemisia absinthium.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Reference standards.

In vitro:

Pharmaceutical Biology, 2008, 43(4):378-381.

A New Larvicidal Lignan from Piper fimbriulatum.[Reference: WebLink]

METHODS AND RESULTS:
A new lignan, 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan (1) (6-[4-(3,4-dimethoxy-phenyl)-tetrahydro-furo[3,4-c.]furan-1-yl]-4-methoxy-benzo[] dioxole) together with two known lignans, 7′-epi.-sesartemin (2) and diayangambin (3), and a known flavonoid, 5-hydroxy-7,4′-dimethoxyflavone (4), were isolated from the leaves of Piper fimbriulatum. C. DC. Their structures were assigned by a combination of one- and two-dimensional NMR techniques.
CONCLUSIONS:
7′-epi.-Sesartemin (2) showed the highest larvicidal activity against Aedes aegypti. (LC100 17.6 µg/ml) and weak antiplasmodial (IC50 7.0 µg/ml) and antitrypanosomal (IC50 39.0 µg/ml) activities. None of the compounds was active against Leishmania mexicana..

3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan Description

Source:	The roots of Artemisia absinthium.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Lignans Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.4974 mL	12.4869 mL	24.9738 mL	49.9476 mL	62.4344 mL
5 mM	0.4995 mL	2.4974 mL	4.9948 mL	9.9895 mL	12.4869 mL
10 mM	0.2497 mL	1.2487 mL	2.4974 mL	4.9948 mL	6.2434 mL
50 mM	0.0499 mL	0.2497 mL	0.4995 mL	0.999 mL	1.2487 mL
100 mM	0.025 mL	0.1249 mL	0.2497 mL	0.4995 mL	0.6243 mL

CFN92432	8-Hydroxypinoresinol	81426-17-7	374.4	C₂₀H₂₂O₇
CFN00449	8-Acetoxypinoresinol	81426-14-4	416.43	C₂₂H₂₄O₈
CFN90676	Herpetone	951677-22-8	522.54	C₂₉H₃₀O₉
CFN96416	Yangambin	13060-14-5	446.49	C₂₄H₃₀O₈
CFN96723	Epiyangambin	24192-64-1	446.49	C₂₄H₃₀O₈
CFN98775	Pinoresinol	487-36-5	358.4	C₂₀H₂₂O₆
CFN90879	Pinoresinol dimethyl ether	29106-36-3	386.4	C₂₂H₂₆O₆
CFN96266	Eudesmin	526-06-7	386.4	C₂₂H₂₆O₆
CFN96935	3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan	873867-94-8	400.42	C₂₂H₂₄O₇
CFN98420	Pinoresinol diacetate	32971-25-8	442.5	C₂₄H₂₆O₈