3,4,5-Trimethoxycinnamyl alcohol | CAS:30273-62-2

3,4,5-Trimethoxycinnamyl alcohol

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Product Name	3,4,5-Trimethoxycinnamyl alcohol
Price:
CAS No.:	30273-62-2
Catalog No.:	CFN98379
Molecular Formula:	C₁₂H₁₆O₄
Molecular Weight:	224.3 g/mol
Purity:	>=98%
Type of Compound:	Phenylpropanoids
Physical Desc.:	Oil
Source:	The roots of Acorus gramineus.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

3,4,5-Trimethoxycinnamyl alcohol shows significant antimicrobial and cytotoxic activities.

Targets:

Antifection

In vitro:

Fitoterapia. 2003 Apr;74(3):308-11.

Antimicrobial and cytotoxic constituents of Loranthus globosus.[Pubmed: 12727502]

METHODS AND RESULTS:
(+)-Catechin, 3,4-dimethoxycinnamyl alcohol and 3,4,5-Trimethoxycinnamyl alcohol were isolated from the barks of Loranthus globosus. All compounds showed significant antimicrobial and cytotoxic activities.

In vivo:

Pak J Biol Sci. 2007 Jun 15;10(12):2073-7.

Toxicological studies of two compounds isolated from Loranthus globosus Roxb.[Pubmed: 19093449]

METHODS AND RESULTS:
The sub-acute toxicities of two compounds 3,4-dimethoxycinnamyl alcohol (1) and 3,4,5-Trimethoxycinnamyl alcohol (2) isolated from the plant Loranthus globosus Roxb were studied on long Evan's rats. The studies included the gross general observation such as changes in body weight, haematological profiles [total count of Red Blood Cells (RBC) and White Blood Cells (WBC), differential count of WBC, platelet count and Haemoglobin (Hb)%], biochemical parameters of blood [Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Transaminase (SGPT), Serum Alkaline Phosphatase (SALP), urea and creatinine) and histopathology of the liver, kidney, heart and lung of both control and experimental groups of rats. The changes in haematological and biochemical parameters were statistically not significant after the administration of compounds 1 and 2 in a dose of 300 microg/rat/day for consecutive 14 days. No abnormality was found in the histopathology of the liver, kidney, heart and lung in the experimental groups of rats following same dose when compared with control group.
CONCLUSIONS:
This preliminary study suggests that the isolated compounds may be used safely for clinical trial.

3,4,5-Trimethoxycinnamyl alcohol Description

Source:	The roots of Acorus gramineus.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antibacterial Compound Library Cytotoxic Compound Library Phenylpropanoids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.4583 mL	22.2916 mL	44.5831 mL	89.1663 mL	111.4579 mL
5 mM	0.8917 mL	4.4583 mL	8.9166 mL	17.8333 mL	22.2916 mL
10 mM	0.4458 mL	2.2292 mL	4.4583 mL	8.9166 mL	11.1458 mL
50 mM	0.0892 mL	0.4458 mL	0.8917 mL	1.7833 mL	2.2292 mL
100 mM	0.0446 mL	0.2229 mL	0.4458 mL	0.8917 mL	1.1146 mL

CFN98379	3,4,5-Trimethoxycinnamyl alcohol	30273-62-2	224.3	C₁₂H₁₆O₄
CFN98675	3-Phenyl-2-propen-1-ol	4407-36-7	134.2	C₉H₁₀O
CFN98057	Cinnamyl acetate	21040-45-9	176.2	C₁₁H₁₂O₂
CFN99037	3-(4-Hydroxyphenyl)-1-propanol	10210-17-0	152.2	C₉H₁₂O₂
CFN96011	p-Coumaryl alcohol	3690-05-9	150.2	C₉H₁₀O₂
CFN89230	4-Methoxycinnamyl alcohol	53484-50-7	164.20	C₁₀H₁₂O₂
CFN92410	trans-3,4-Methylenedioxycinnamyl alcohol	58095-76-4	178.2	C₁₀H₁₀O₃
CFN97760	Coniferyl alcohol	32811-40-8	180.20	C₁₀H₁₂O₃
CFN96742	Dihydroconiferyl alcohol	2305-13-7	182.21	C₁₀H₁₄O₃
CFN96094	Gamma-Methoxyisoeugenol	63644-71-3	194.2	C₁₁H₁₄O₃