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Biorobin
Biorobin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Biorobin
Price:
CAS No.: 17297-56-2
Catalog No.: CFN97804
Molecular Formula: C27H30O15
Molecular Weight: 594.53 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The herbs of Cassia occidentalis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
Planta Med. 2008 Feb;74(2):171-4.
Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana.[Pubmed: 18214815]

METHODS AND RESULTS:
The flavonoids kaempferol, quercetin, trifolin, hyperoside 2''- and 6''- acetates, 7-glucotrifolin, Biorobin and robinin were isolated from the aerial parts of Consolida oliveriana.
CONCLUSIONS:
Their derivatives kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity IN VITRO against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2''-acetate, hyperoside-6''-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.
Biorobin Description
Source: The herbs of Cassia occidentalis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.682 mL 8.41 mL 16.82 mL 33.64 mL 42.05 mL
5 mM 0.3364 mL 1.682 mL 3.364 mL 6.728 mL 8.41 mL
10 mM 0.1682 mL 0.841 mL 1.682 mL 3.364 mL 4.205 mL
50 mM 0.0336 mL 0.1682 mL 0.3364 mL 0.6728 mL 0.841 mL
100 mM 0.0168 mL 0.0841 mL 0.1682 mL 0.3364 mL 0.4205 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Fitoterapia. 2006 Sep;77(6):484-6.
Flavonoids from Acalypha indica.[Pubmed: 16828241]

METHODS AND RESULTS:
Four known kaempferol glycosides, mauritianin, clitorin, nicotiflorin and Biorobin, have been isolated from the flowers and leaves of Acalypha indica. Some formerly published NMR data were corrected.
CFN95366Ternatumoside II1473419-87-2594.5C27H30O15
CFN90342Helicianeoide A496066-82-1726.63C32H38O19
CFN91162Kaempferol-3-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside476617-49-9756.7C33H40O20
CFN93560Camelliaside B131573-90-5726.6C32H38O19
CFN90819Mauritianin109008-28-8740.7C33H40O19
CFN93559Camelliaside A135095-52-2756.66C33H40O20
CFN91161Plantanone B55780-30-8756.7C33H40O20
CFN96532Kaempferol 3-O-rhamninoside83170-31-4740.66C33H40O19
CFN95134Rhamnocitrin 3-glucoside41545-37-3462.4C22H22O11
CFN95474Rhamnocitrin 3-galactoside99878-05-4462.4C22H22O11
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