Science | Nature | Cell | View More
Natural Products
3-Hydroxybenzaldehyde
3-Hydroxybenzaldehyde
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 3-Hydroxybenzaldehyde
Price: $30 / 20mg
CAS No.: 100-83-4
Catalog No.: CFN70002
Molecular Formula: C7H6O2
Molecular Weight: 122.1 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Amsterdam (Netherlands)
  • Celltrion Chemical Research Ins... (Korea)
  • University of Canterbury (New Zealand)
  • Colorado State University (USA)
  • Universidad Miguel Hernández (Spain)
  • Pennsylvania State University (USA)
  • University of Beira Interior (Portugal)
  • University of British Columbia (Canada)
  • China Medical University (Taiwan)
  • University of Padjajaran (Indonesia)
  • University of Zurich (Switzerland)
  • More...
Package
Featured Products
L-Alanine

Catalog No: CFN70145
CAS No: 56-41-7
Price: $30/20mg
Benzoylhypacoitine

Catalog No: CFN90688
CAS No: 63238-66-4
Price: $188/20mg
Aloin B

Catalog No: CFN90434
CAS No: 28371-16-6
Price: $138/20mg
Ginsenoside Ro

Catalog No: CFN99147
CAS No: 34367-04-9
Price: $100/20mg
Linolenic acid

Catalog No: CFN70110
CAS No: 463-40-1
Price: $30/20mg
Ganoderic acid C2

Catalog No: CFN92054
CAS No: 103773-62-2
Price: $318/20mg
(+)-Taxifolin

Catalog No: CFN99183
CAS No: 17654-26-1
Price: $70/20mg
Cryptochlorogenic acid

Catalog No: CFN99117
CAS No: 905-99-7
Price: $90/20mg
Strictosamide

Catalog No: CFN98237
CAS No: 23141-25-5
Price: $158/10mg
Narcissoside

Catalog No: CFN99773
CAS No: 604-80-8
Price: $70/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 3-Hydroxybenzaldehyde, a novel therapeutic agent, has shown vasculoprotective potency in both in vitro and in vivo. 3-Hydroxybenzaldehyde has antioxidant and antibacterial activityies.
Targets: Antifection
In vitro:
Iet Nanobiotechnology, 2017, 11(6):630-636.
Antioxidant and antibacterial activity evaluation of 3-hydroxybenzaldehyde: The product of thymol oxidation by a new magnetic nanocatalyst.[Reference: WebLink]
In this study maghemite nanoparticles were synthesised, they were first coated by sodium alginate and then by chitosan.
METHODS AND RESULTS:
Then acetanilide was introduced to maghemite nanoparticles that were coated by alginate and chitosan. Finally a silver complex was made with acetanilide and the magnetic nanocatalyst was synthesised. This nanocatalyst was used for the oxidation of thymol, then antioxidant and antibacterial properties of the oxidation product were assessed. Characterisation of this nanocatalyst was performed by Fourier transform infrared spectroscopy (FT-IR), X-ray diffractometer, scanning electron microscope (SEM) and value stream mapping. Creation of the product was confirmed by FT-IR and gas chromatography-mass spectroscopy. According to SEM, the size of the nanocatalyst was in the range of 46-70 nm. 3-Hydroxybenzaldehyde was obtained from the oxidation of thymol.
CONCLUSIONS:
It had antioxidant property as evident from Di (phenyl) -(2, 4, 6-trinitrophenyl) iminoazanium and the Folin-Ciocalteu method. Diffusion and dilution methods were used for the evaluation of the antibacterial activity. It was obvious from MIC that gram negative strains were more resistant than gram positive ones, and from minimum bactericidal concentration, it was obvious that Escherichia coli was the most resistant gram negative strain, and Bacillus subtilis was the most resistant gram positive strain.
Plos One, 2016, 11(3):e0149394.
Vasculoprotective Effects of 3-Hydroxybenzaldehyde against VSMCs Proliferation and ECs Inflammation.[Pubmed: 27002821]
3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for phenolic compounds like Protocatechuic aldehyde (PCA). From recent reports, PCA has shown vasculoprotective potency, but the effects of 3-HBA remain unclear. The aim of this study is to investigate the vasculoprotective effects of 3-HBA in endothelial cells, vascular smooth muscle cells and various animal models.
METHODS AND RESULTS:
We tested effects of 3-HBA in both vitro and vivo. 3-HBA showed that it prevents PDGF-induced vascular smooth muscle cells (VSMCs) migration and proliferation from MTS, BrdU assays and inhibition of AKT phosphorylation. It arrested S and G0/G1 phase of VSMC cell cycle in PI staining and it also showed inhibited expression levels of Rb1 and CD1. In human umbilical vein endothelial cells (HUVECs), 3-HBA inhibited inflammatory markers and signaling molecules (VCAM-1, ICAM-1, p-NF-κB and p-p38). For ex vivo, 3-HBA has shown dramatic effects in suppressing the sprouting from aortic ring of Spargue Dawley (SD) rats. In vivo data supported the vasculoprotective effects of 3-HBA as it inhibited angiogenesis from Matrigel Plug assay in C57BL6 mouse, prevented ADP-induced thrombus generation, increased blood circulation after formation of thrombus, and attenuated neointima formation induced by common carotid artery balloon injury of SD rats.
CONCLUSIONS:
3-HBA, a novel therapeutic agent, has shown vasculoprotective potency in both in vitro and in vivo.
3-Hydroxybenzaldehyde Description
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Giganteone A

Catalog No: CFN95481
CAS No: 460337-13-7
Price: $318/5mg
2-Methoxy-1,4-naphthoquinone

Catalog No: CFN95269
CAS No: 2348-82-5
Price: $70/20mg
1-O-galloyl-6-O-cinnamoylglucose

Catalog No: CFN95053
CAS No: 115746-69-5
Price: $338/5mg
Decuroside I

Catalog No: CFN95004
CAS No: 96638-79-8
Price: $318/5mg
Aromadendrene

Catalog No: CFN95074
CAS No: 489-39-4
Price: $40/20mg
5,6,7,3',4'-Pentamethoxyflavanone

Catalog No: CFN95394
CAS No: 104193-93-3
Price: $318/5mg
Cannabiscitrin

Catalog No: CFN95278
CAS No: 520-14-9
Price: $318/5mg
11alpha-hydroxy-3,7-dioxo-5alpha-l...

Catalog No: CFN95592
CAS No: 1245703-70-1
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 8.19 mL 40.95 mL 81.9001 mL 163.8002 mL 204.7502 mL
5 mM 1.638 mL 8.19 mL 16.38 mL 32.76 mL 40.95 mL
10 mM 0.819 mL 4.095 mL 8.19 mL 16.38 mL 20.475 mL
50 mM 0.1638 mL 0.819 mL 1.638 mL 3.276 mL 4.095 mL
100 mM 0.0819 mL 0.4095 mL 0.819 mL 1.638 mL 2.0475 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
L-Alanine

Catalog No: CFN70145
CAS No: 56-41-7
Price: $30/20mg
Benzoylhypacoitine

Catalog No: CFN90688
CAS No: 63238-66-4
Price: $188/20mg
Aloin B

Catalog No: CFN90434
CAS No: 28371-16-6
Price: $138/20mg
Ginsenoside Ro

Catalog No: CFN99147
CAS No: 34367-04-9
Price: $100/20mg
Linolenic acid

Catalog No: CFN70110
CAS No: 463-40-1
Price: $30/20mg
Ganoderic acid C2

Catalog No: CFN92054
CAS No: 103773-62-2
Price: $318/20mg
(+)-Taxifolin

Catalog No: CFN99183
CAS No: 17654-26-1
Price: $70/20mg
Cryptochlorogenic acid

Catalog No: CFN99117
CAS No: 905-99-7
Price: $90/20mg
Strictosamide

Catalog No: CFN98237
CAS No: 23141-25-5
Price: $158/10mg
Narcissoside

Catalog No: CFN99773
CAS No: 604-80-8
Price: $70/20mg
Tags: buy 3-Hydroxybenzaldehyde | 3-Hydroxybenzaldehyde supplier | purchase 3-Hydroxybenzaldehyde | 3-Hydroxybenzaldehyde cost | 3-Hydroxybenzaldehyde manufacturer | order 3-Hydroxybenzaldehyde | 3-Hydroxybenzaldehyde distributor