Aloin B | CAS:28371-16-6 | Manufacturer ChemFaces

Aloin B

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $29.6 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Complanatoside B

Catalog No: CFN80156
CAS No: 142473-99-2
Price: $218/10mg

Moracin D

Catalog No: CFN97179
CAS No: 69120-07-6
Price: $ /

Quercitrin

Catalog No: CFN98850
CAS No: 522-12-3
Price: $40/20mg

Guanosine

Catalog No: CFN90925
CAS No: 118-00-3
Price: $30/20mg

Siamenoside I

Catalog No: CFN90398
CAS No: 126105-12-2
Price: $338/20mg

Pelargonidin-3-O-glucoside chloride

Catalog No: CFN92134
CAS No: 18466-51-8
Price: $490/10mg

20(R)-Ginsenoside Rh2

Catalog No: CFN90340
CAS No: 112246-15-8
Price: $70/20mg

Bakuchalcone

Catalog No: CFN92229
CAS No: 84575-13-3
Price: $ / mg

Alisol A

Catalog No: CFN92542
CAS No: 19885-10-0
Price: $80/20mg

Celastrol

Catalog No: CFN99198
CAS No: 34157-83-0
Price: $40/20mg

Description:

Dietary supplementation of aloe components (aloin, aloesin and aloe-gel) can ameliorate intestinal inflammatory responses in a 3% dextran sulfate sodium (DSS)-induced ulcerative colitis rat model, in particular, aloesin is the most potent inhibitor. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation.

In vitro:

J AOAC Int. 2014 Sep-Oct;97(5):1323-8.

Determination of Aloin A and Aloin B in Aloe vera Raw Materials and Finished Products by High-Performance Liquid Chromatography: Single-Laboratory Validation.[Pubmed: 25902982]

A single-laboratory validation (SLV) was conducted on an HPLC method for the detection and quantification of aloin A and Aloin B in Aloe vera raw materials and finished products.
METHODS AND RESULTS:
An extraction procedure using sonication with an acidified solvent was used for solid test materials while liquid test materials only required dilution, if necessary, prior to filtration and analysis. Separation was achieved using a fused core C18 column in 18 min under isocratic elution conditions allowing for a single analyte (aloin A) calibration curve to quantify both aloins. Adequate chromatographic resolution (Rs ≥1) was achieved for aloin A and Aloin B. The calibration curves for aloin A exhibited coefficients of determination (r(2)) of ≥99.9% over the linear range of 0.3-50 μg/mL.
CONCLUSIONS:
The LOD values were 0.092 and 0.087 μg/mL, and LOQ 0.23 and 0.21 μg/mL for aloin A and Aloin B, respectively.

Aloin B Description

Source:	The herbs of Aloe vera L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Advanced Materials Research, Vols. 634-638, pp. 1241-1246, Jan. 2013

Isolation and Purification of Aloin a and Aloin B by High-Speed Counter-Current Chromatography[Reference: WebLink]

METHODS AND RESULTS:
High-speed counter-current chromatography(HSCCC) was successfully used for isolation and purification of Aloin A and Aloin B from the crude methanol extract of Aloe with a two-phase solvent system composed of chloroform–methanol–n-butylalcohol-water at an optimized volume ratio of 4:3:1:2 (v/v/v/v). The lower phase was used as the mobile phase in the head to tail elution mode. The preparative HSCCC separation was performed on 180 mg of the crude extract yielding pure Aloin A(18mg) and Aloin B(16mg) at purities of 95.2% and 96.8%, respectively, as determined by high performance liquid chromatography (HPLC).
CONCLUSIONS:
HSCCC is a powerful technique for isolation and separation of chemical composition from aloe.

Product Name	Aloin B
Price:	$138 / 20mg
CAS No.:	28371-16-6
Catalog No.:	CFN90434
Molecular Formula:	C₂₁H₂₂O₉
Molecular Weight:	418.39 g/mol
Purity:	>=98%
Type of Compound:	Anthraquinones
Physical Desc.:	Yellow powder
Source:	The herbs of Aloe vera L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-inflammatory Compound Library Dietary supplement Compound Library Skin-lightening agents Compound Library Anti-melanogenic Compound Library Anthraquinones Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3901 mL	11.9506 mL	23.9011 mL	47.8023 mL	59.7529 mL
5 mM	0.478 mL	2.3901 mL	4.7802 mL	9.5605 mL	11.9506 mL
10 mM	0.239 mL	1.1951 mL	2.3901 mL	4.7802 mL	5.9753 mL
50 mM	0.0478 mL	0.239 mL	0.478 mL	0.956 mL	1.1951 mL
100 mM	0.0239 mL	0.1195 mL	0.239 mL	0.478 mL	0.5975 mL

CFN91461	Aloinoside B	11006-91-0	564.5	C₂₇H₃₂O₁₃
CFN95453	Barbaloin-related compound A	473225-21-7	834.8	C₄₂H₄₂O₁₈
CFN95455	Barbaloin-related compound B	473225-22-8	834.8	C₄₂H₄₂O₁₈
CFN70403	Cascaroside A	53823-08-8	580.5	C₂₇H₃₂O₁₄
CFN93123	Aloe-emodin-8-O-beta-D-glucopyranoside	33037-46-6	432.4	C₂₁H₂₀O₁₀
CFN99410	Chrysophanol 8-O-glucoside	13241-28-6	416.4	C₂₁H₂₀O₉
CFN91463	Chrysophanol-8-O-beta-D-(6'-O-galloyl)-glucopyranoside	266997-57-3	568.5	C₂₈H₂₄O₁₃
CFN93322	Chrysophanol 1-O-glucoside	4839-60-5	416.38	C₂₁H₂₀O₉
CFN91124	Chrysophanol 1-O-beta-tetraglucoside	120181-08-0	902.8	C₃₉H₅₀O₂₄
CFN93238	Emodin 1-O-beta-D-glucoside	38840-23-2	432.38	C₂₁H₂₀O₁₀