5-Methoxy-7-hydroxycoumarin | CAS:3067-10-5

5-Methoxy-7-hydroxycoumarin

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5-Methoxy-7-hydroxycoumarin Description

Source:	The peels of Citrus medica L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Kinase Assay:

J. Biol. Sci., 2005, 5(4):525-31.

Comparative Effects of Scopoletin and Menadione on Aldehyde Oxidase Activity of Guinea Pig Liver[Reference: WebLink]

Scopoletin, 7-hydroxy-5-methoxycoumarin(5-Methoxy-7-hydroxycoumarin ), has been found to be a moderate inhibitor for aldehyde oxidase, a molybdo-flavoenzymes. It inhibits the release of superoxide anion more efficiently than hydrogen peroxide or substrate oxidation.
METHODS AND RESULTS:
Statistically, the inhibition of three-specific aldehyde oxidase substrates was significant (p<0.005) in the presence of 100 uM Scopoletin. A progressive and non-competitive inhibition has been observed with inhibitor constant (Ki) value of 57.2 uM using indole-3-aldehyde and oxygen as a substrate and electron acceptor, respectively. A specific site for interaction between Scopoletin and aldehyde oxidase has been proposed and its effect on the reactive oxygen species production has been discussed.
CONCLUSIONS:
The effect of Scopoletin on aldehyde oxidase activity has been compared with that of traditional and specific inhibitors, such as menadione.

Product Name	5-Methoxy-7-hydroxycoumarin
Price:
CAS No.:	3067-10-5
Catalog No.:	CFN92630
Molecular Formula:	C₁₀H₈O₄
Molecular Weight:	192.2 g/mol
Purity:	>=98%
Type of Compound:	Coumarins
Physical Desc.:	Powder
Source:	The peels of Citrus medica L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antifeedant Compound Library Coumarins Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.2029 mL	26.0146 mL	52.0291 mL	104.0583 mL	130.0728 mL
5 mM	1.0406 mL	5.2029 mL	10.4058 mL	20.8117 mL	26.0146 mL
10 mM	0.5203 mL	2.6015 mL	5.2029 mL	10.4058 mL	13.0073 mL
50 mM	0.1041 mL	0.5203 mL	1.0406 mL	2.0812 mL	2.6015 mL
100 mM	0.052 mL	0.2601 mL	0.5203 mL	1.0406 mL	1.3007 mL

CFN92630	5-Methoxy-7-hydroxycoumarin	3067-10-5	192.2	C₁₀H₈O₄
CFN97963	Citropten	487-06-9	206.2	C₁₁H₁₀O₄
CFN99003	7-Geranyloxy-5-methoxycoumarin	1432075-68-7	328.4	C₂₀H₂₄O₄
CFN70446	5-Geranoxy-7-methoxycoumarin	7380-39-4	328.4	C₂₀H₂₄O₄
CFN92666	6-Hydroxymethylherniarin	117597-79-2	206.2	C₁₁H₁₀O₄
CFN97325	7-Hydroxycoumarin-6-carboxylic acid	833-52-3	206.2	C₁₀H₆O₅
CFN92511	6-Formyllimetin	88140-31-2	234.2	C₁₂H₁₀O₅