6-O-(3'',4''-Dimethoxycinnamoyl)catalpol | CAS:147714-71-4

6-O-(3'',4''-Dimethoxycinnamoyl)catalpol

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Description:

6-O-(3'',4''-Dimethoxycinnamoyl)catalpol has anti-hepatotoxic activity.

In vitro:

Z Naturforsch C. 2009 Jan-Feb;64(1-2):11-9.

Antihepatotoxic activity and chemical constituents of Buddleja asiatica Lour.[Pubmed: 19323260]

METHODS AND RESULTS:
A new natural compound, named 6-O-(3'',4''-Dimethoxycinnamoyl)catalpol , was isolated from the defatted alcoholic extract of the flowering parts of Buddleja asiatica Lour. (family Scrophulariaceae). Other separated known compounds included steroids (beta-sitosterol, stigmasterol, stigmasterol-O-glucoside, beta-sitosterol-O-glucoside), iridoid glucosides (methyl catalpol, catalpol, aucubin), phenylpropanoids (isoacteoside and acteoside), a triterpene saponin (mimengoside A), flavonoids (diosmin and linarin) in addition to the free sugars mannitol and sucrose.
CONCLUSIONS:
The structures of the isolated compounds were established by 1H and 13C NMR and mass spectrometry. Furthermore, the polar fraction of the flowering parts and the roots showed substantial antihepatotoxic activity comparable to that of the lignan silymarin.

6-O-(3'',4''-Dimethoxycinnamoyl)catalpol Description

Source:	The herbs of Buddleja asiatica Lour
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	6-O-(3'',4''-Dimethoxycinnamoyl)catalpol
Price:
CAS No.:	147714-71-4
Catalog No.:	CFN99611
Molecular Formula:	C₂₆H₃₂O₁₃
Molecular Weight:	552.5 g/mol
Purity:	>=98%
Type of Compound:	Iridoids
Physical Desc.:	Powder
Source:	The herbs of Buddleja asiatica Lour
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Hepatoprotective Compound Library Iridoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.81 mL	9.0498 mL	18.0995 mL	36.1991 mL	45.2489 mL
5 mM	0.362 mL	1.81 mL	3.6199 mL	7.2398 mL	9.0498 mL
10 mM	0.181 mL	0.905 mL	1.81 mL	3.6199 mL	4.5249 mL
50 mM	0.0362 mL	0.181 mL	0.362 mL	0.724 mL	0.905 mL
100 mM	0.0181 mL	0.0905 mL	0.181 mL	0.362 mL	0.4525 mL

CFN99428	6-O-Cinnamoylcatalpol	136807-41-5	492.5	C₂₄H₂₈O₁₁
CFN99565	Picroside I	27409-30-9	492.47	C₂₄H₂₈O₁₁
CFN97207	Specioside	72514-90-0	508.5	C₂₄H₂₈O₁₂
CFN99335	6-O-p-Methoxycinnamoylcatalpol	121710-02-9	522.5	C₂₅H₃₀O₁₂
CFN98809	Verminoside	50932-19-9	524.5	C₂₄H₂₈O₁₃
CFN97255	6-Feruloylcatalpol	770721-33-0	538.5	C₂₅H₃₀O₁₃
CFN98811	Minecoside	51005-44-8	538.5	C₂₅H₃₀O₁₃
CFN99611	6-O-(3'',4''-Dimethoxycinnamoyl)catalpol	147714-71-4	552.5	C₂₆H₃₂O₁₃
CFN90868	Picroside IV	211567-04-3	508.50	C₂₄H₂₈O₁₂
CFN99567	Picroside III	64461-95-6	538.50	C₂₅H₃₀O₁₃