7-O-Methyleriodictyol | CAS:51857-11-5

7-O-Methyleriodictyol

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Description:

7-O-Methyleriodictyol inhibits the maximum contractions induced by acetylcholine or oxytocin.

Targets:

AChR

In vivo:

Planta Med. 1993 Feb;59(1):42-5.

Isolation and biological effects of 7-O-methyleriodictyol, a flavanone isolated from Artemisia monosperma, on rat isolated smooth muscles.[Pubmed: 8441781]

METHODS AND RESULTS:
The isolation for the first time from the genus Artemisia (Compositae) of the known flavanone, 7-O-Methyleriodictyol (7-methoxy-5,3',4'-trihydroxy-flavanone), its identification, and its biological effects on rat isolated smooth muscles are described. 7-O-Methyleriodictyol (10(-7) M to 3 x 10(-4) M) caused concentration-dependent inhibition of the amplitude of the phasic contractions and reduced the tone of the ileum, the uterus, and the urinary bladder. It also caused relaxation of the phenylephrine-precontracted pulmonary artery and the acetylcholine-precontracted trachea. The flavanone also shifted to the right the acetylcholine concentration-effect curve on the ileum and the oxytocin concentration-effect curve on the uterus. The maximum contractions induced by acetylcholine or oxytocin were also inhibited by 7-O-Methyleriodictyol.
CONCLUSIONS:
These antispasmodic effects are partly consistent with the use of A. monosperma in folk medicine for certain gastrointestinal disorders.

7-O-Methyleriodictyol Description

Source:	The branches of Viscum coloratum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	7-O-Methyleriodictyol
Price:
CAS No.:	51857-11-5
Catalog No.:	CFN98833
Molecular Formula:	C₁₆H₁₄O₆
Molecular Weight:	302.3 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The branches of Viscum coloratum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-spasmodic Compound Library Flavonoids Compound Library AChR Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.308 mL	16.5399 mL	33.0797 mL	66.1594 mL	82.6993 mL
5 mM	0.6616 mL	3.308 mL	6.6159 mL	13.2319 mL	16.5399 mL
10 mM	0.3308 mL	1.654 mL	3.308 mL	6.6159 mL	8.2699 mL
50 mM	0.0662 mL	0.3308 mL	0.6616 mL	1.3232 mL	1.654 mL
100 mM	0.0331 mL	0.1654 mL	0.3308 mL	0.6616 mL	0.827 mL

CFN90850	Isookanin	1036-49-3	288.3	C₁₅H₁₂O₆
CFN91006	Flavanomarein	577-38-8	450.4	C₂₁H₂₂O₁₁
CFN96496	Plathymenin	492-12-6	288.25	C₁₅H₁₂O₆
CFN99719	Eriodictyol	552-58-9	288.25	C₁₅H₁₂O₆
CFN98833	7-O-Methyleriodictyol	51857-11-5	302.3	C₁₆H₁₄O₆
CFN96489	Homoeriodictyol	446-71-9	302.28	C₁₆H₁₄O₆
CFN89421	Viscumneoside III	118985-27-6	596.53	C₂₇H₃₂O₁₅
CFN89533	Eriodictyol 7,3'-dimethyl ether	54352-60-2	316.30	C₁₇H₁₆O₆
CFN98842	Hesperetin	520-33-2	302.3	C₁₆H₁₄O₆
CFN90876	Hesperetin-7-methyl ether	N/A	316.3	C₁₇H₁₆O₆