8-Prenylluteone | CAS:125002-91-7 | Manufacturer ChemFaces

8-Prenylluteone

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Description:

8-Prenylluteone can potently inhibit HIV-1 PR activity.

Targets:

HIV

In vitro:

Planta Med. 2009 Feb;75(3):268-70.

Prenylisoflavonoids from Erythrina senegalensis as novel HIV-1 protease inhibitors.[Pubmed: 19097000 ]

Eight compounds were isolated from the CH (2)Cl (2) extracts of ERYTHRINA SENEGALENSIS to assess HIV-1 protease (PR) activity inhibition.
METHODS AND RESULTS:
The prenylated isoflavone structures, identified by spectroscopic analysis, were 8-Prenylluteone ( 1), auriculatin ( 2), erysenegalensein O ( 3), erysenegalensein D ( 4), erysenegalensein N ( 5), derrone ( 6), alpinumisoflavone ( 7), and 6,8-diprenylgenistein ( 8). The constituents showed dose-dependent inhibitory activities on HIV-1 PR with IC (50) values from 0.5 to 30.0 muM.
CONCLUSIONS:
Compounds 1 - 5 possessing two hydroxy groups in the 2' and 4' positions of the B ring, potently inhibited HIV-1 PR activity. In addition, 6,8-diprenylgenistein ( 8) with two prenyl groups in the 6 and 8 positions of the A ring and one hydroxy group in the 4' position of B-ring was the most potent HIV-1 PR inhibitor.

8-Prenylluteone Description

Source:	The herbs of Erythrina stricta
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	8-Prenylluteone
Price:
CAS No.:	125002-91-7
Catalog No.:	CFN97899
Molecular Formula:	C₂₅H₂₆O₆
Molecular Weight:	422.5 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Erythrina stricta
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Antiviral Compound Library Flavonoids Compound Library HIV Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3669 mL	11.8343 mL	23.6686 mL	47.3373 mL	59.1716 mL
5 mM	0.4734 mL	2.3669 mL	4.7337 mL	9.4675 mL	11.8343 mL
10 mM	0.2367 mL	1.1834 mL	2.3669 mL	4.7337 mL	5.9172 mL
50 mM	0.0473 mL	0.2367 mL	0.4734 mL	0.9467 mL	1.1834 mL
100 mM	0.0237 mL	0.1183 mL	0.2367 mL	0.4734 mL	0.5917 mL

CFN97245	Lupalbigenin	76754-24-0	406.5	C₂₅H₂₆O₅
CFN97894	Isochandalone	121747-90-8	404.5	C₂₅H₂₄O₅
CFN96071	Isoerysenegalensein E	478158-77-9	422.5	C₂₅H₂₆O₆
CFN96072	Erysenegalensein E	154992-17-3	422.48	C₂₅H₂₆O₆
CFN97935	6,8-Diprenylgenistein	51225-28-6	406.5	C₂₅H₂₆O₅
CFN97917	Osajin	482-53-1	404.5	C₂₅H₂₄O₅
CFN97899	8-Prenylluteone	125002-91-7	422.5	C₂₅H₂₆O₆
CFN96200	Millewanin G	874303-33-0	438.5	C₂₅H₂₆O₇
CFN96205	Millewanin H	874303-34-1	438.5	C₂₅H₂₆O₇
CFN97705	6,8-Diprenylorobol	66777-70-6	422.48	C₂₅H₂₆O₆