| Structure Identification: |
| Journal of the Chinese Chemical Society, 2013 , 49 (3) :433-6. | | Chemical Constituents of the Aerial Part of Celastrus Hypoleucus[Reference: WebLink] |
METHODS AND RESULTS:
Fourteen compounds including eight triterpenoids, 12-oleanaen-3beta-ol (beta-amyrin) (1), 12-oleanaen-3beta-caffeate (2), 9(11),12-oleanadien-3beta-ol (9(11),12-Oleanadien-3-ol,3), 9(11),12-oleanadien-3-one (4), 9(11),12-oleanadien-3beta-caffeate (5), friedela-3-one (friedelin) (6), friedela-3-one-29-ol (7), and 12-gammateraen-3beta-ol (tetrehymanol) (8); one steroid, beta-sitosterol (9); one long-chain acid, octadecadienoic acid (10); two esters, ester of n-octaolecyl-4-hydroxy-cinnamate (11), and ester of n-octadecyl-caffeic acid (12); one diterpene, 8beta,19-dihydroxy-3-oxopimar- 15-ene (13); one sesquiterpene, 1beta,2beta,9alpha-trihydroxy-beta-dihydroagarofuran (14) were isolated from the aerial part of Celastrus hypoleucus, These compounds were characterized and identified by physical and spectral methods.
CONCLUSIONS:
All compounds were isolated for the first time from this plant. Among them 12-oleanaen-3beta- caffeate (2) and 9(11),12-oleanadien-3beta-caffeate (5) are two new compounds, and ester of n-octadecyl-caffeic acid (12) possessed antilipoperoxidative effect by specifically scavenging the hydroxyl free radical (.OH) in vitro. |
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