Albaspidin AA | CAS:3570-40-9 | Manufacturer ChemFaces

Albaspidin AA

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Albaspidin AA displays strong antibacterial activity against the vegetative form of P. larvae (MIC ranging from 0.168-220 uM). It may have in vitro nematocidal activity against L4 stage larvae.

Targets:

Antifection

In vitro:

Phytochemistry. 2012 Aug;80:115-22.

Unusual terpenylated acylphloroglucinols from Dryopteris wallichiana.[Pubmed: 22658282 ]

METHODS AND RESULTS:
Four unusual terpenylated acylphloroglucinols were isolated from the diethyl ether extract of the scales and rhizomes of the fern Dryopteris wallichiana together with the known compounds Albaspidin AA and albaspidin AB, and filixic acids ABA and ABB. Structures of the isolated compounds were established by extensive spectroscopic analysis and their absolute configuration at C-14″ was determined by comparing their CD spectra with those simulated for the respective isomers.
CONCLUSIONS:
Pure acylphloroglucinols displayed moderate in vitro nematocidal activity against L4 stage larvae of Nippostrongylus brasiliensis (LD₅₀=22-121 μM).

Albaspidin AA Description

Source:	The rhizomes of Dryopteris crassirhizoma Nakai
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Chem Biodivers. 2014 May;11(5):695-708.

In vitro growth inhibition by Hypericum extracts and isolated pure compounds of Paenibacillus larvae, a lethal disease affecting honeybees worldwide.[Pubmed: 24827680]

METHODS AND RESULTS:
Six pure compounds isolated from these extracts, viz., hyperforin (1), uliginosin B (2), uliginosin A (3), 7-epiclusianone (4), Albaspidin AA (5), and drummondin E (6), displayed strong antibacterial activity against the vegetative form of P. larvae (MIC ranging from 0.168-220 μM).
CONCLUSIONS:
Incubation of P. larvae spores with the lipophilic extract of Hypericum perforatum and its main acylphloroglucinol constituent 1 led to the observation of significantly fewer colony forming units as compared to the negative control, indicating that the acylphloroglucinol scaffold represents an interesting lead structure for the development of new AFB control agents.

Product Name	Albaspidin AA
Price:
CAS No.:	3570-40-9
Catalog No.:	CFN98474
Molecular Formula:	C₂₁H₂₄O₈
Molecular Weight:	404.4 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Yellow powder
Source:	The rhizomes of Dryopteris crassirhizoma Nakai
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antibacterial Compound Library Nematicidal Compound Library Phenols Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.4728 mL	12.364 mL	24.728 mL	49.456 mL	61.82 mL
5 mM	0.4946 mL	2.4728 mL	4.9456 mL	9.8912 mL	12.364 mL
10 mM	0.2473 mL	1.2364 mL	2.4728 mL	4.9456 mL	6.182 mL
50 mM	0.0495 mL	0.2473 mL	0.4946 mL	0.9891 mL	1.2364 mL
100 mM	0.0247 mL	0.1236 mL	0.2473 mL	0.4946 mL	0.6182 mL

CFN92877	Didemethylpseudoaspidin AA	142382-28-3	376.4	C₁₉H₂₀O₈
CFN90684	Pseudoaspidin	478-28-4	460.5	C₂₅H₃₂O₈
CFN98474	Albaspidin AA	3570-40-9	404.4	C₂₁H₂₄O₈
CFN90252	Albaspidin AP	59092-91-0	418.44	C₂₂H₂₆O₈
CFN99573	Filixic acid ABA	38226-84-5	612.63	C₃₂H₃₆O₁₂
CFN98169	Agrimol B	55576-66-4	682.75	C₃₇H₄₆O₁₂
CFN99519	Dryocrassin ABBA	12777-70-7	820.81	C₄₃H₄₈O₁₆
CFN90561	Gossypol	303-45-7	518.56	C₃₀H₃₀O₈
CFN98529	Acetate gossypol	12542-36-8	578.61	C₃₂H₃₄O₁₀
CFN99601	Sideroxylonal A	145382-68-9	500.5	C₂₆H₂₈O₁₀