Alepterolic acid | CAS:63399-38-2 | Manufacturer ChemFaces

Alepterolic acid

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Alepterolic acid Description

Source:	The rhizomes of Cibotium barometz (L.) J.Sm.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Animal Research:

Rev Inst Med Trop Sao Paulo. 2008 Jan-Feb;50(1):25-8.

Diterpenoids from Copaifera reticulata Ducke with larvicidal activity against Aedes aegypti (L.) (Diptera, Culicidae).[Pubmed: 18383630]

The objective of this study was to evaluate the larvicidal activity of diterpenoids obtained from the oil-resin of Copaifera reticulata against Aedes aegypti larvae, the principal vector of dengue and urban yellow fever.
METHODS AND RESULTS:
Four diterpenes were obtained from oil-resin extraction with organic solvents and subsequent chromatographic and spectroscopic procedures allowed to isolation and identification of these compounds as 3-beta-acetoxylabdan-8(17)-13-dien-15-oic acid (1), Alepterolic acid (2), 3-beta-hidroxylabdan-8(17)-en-15-oic acid (3), and ent-agatic acid (4). Each compound was previously dissolved in dimethylsulphoxide, and distilled water was added to obtain the desired concentrations. Twenty larvae of third instars were placed into plastic beckers, containing the solution test (25 mL), in a five repetitions scheme, and their mortality, indicated by torpor and darkening of the cephalic capsule, was recorded after 48 h. Probit analyses were used to determine lethal concentrations (LC50 and LC90) and their respective 95% confidence intervals.
CONCLUSIONS:
This study showed that only diterpenoids 1 and 2 exhibited larvicidal properties with LC50 of 0.8 ppm and 87.3 ppm, respectively, revealing the former as the most toxic compound against third instars of Ae. aegypti. Therefore, this compound seems to be an interesting source for new metabolite to be exploited.

Product Name	Alepterolic acid
Price:
CAS No.:	63399-38-2
Catalog No.:	CFN97091
Molecular Formula:	C₂₀H₃₂O₃
Molecular Weight:	320.5 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The rhizomes of Cibotium barometz (L.) J.Sm.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Insecticides Compound Library Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.1201 mL	15.6006 mL	31.2012 mL	62.4025 mL	78.0031 mL
5 mM	0.624 mL	3.1201 mL	6.2402 mL	12.4805 mL	15.6006 mL
10 mM	0.312 mL	1.5601 mL	3.1201 mL	6.2402 mL	7.8003 mL
50 mM	0.0624 mL	0.312 mL	0.624 mL	1.248 mL	1.5601 mL
100 mM	0.0312 mL	0.156 mL	0.312 mL	0.624 mL	0.78 mL

CFN96361	Metasequoic acid A	113626-22-5	302.5	C₂₀H₃₀O₂
CFN97440	ent-14,15-Dinor-13-oxolabda-8(17),11-dien-18-oic acid	875585-30-1	290.4	C₁₈H₂₆O₃
CFN92778	Coronadiene	1145689-64-0	262.4	C₁₇H₂₆O₂
CFN99058	15-Nor-14-oxolabda-8(17),12-dien-18-oic acid	1039673-32-9	304.4	C₁₉H₂₈O₃
CFN89382	Junicedric acid	41787-69-3	336.46	C₂₀H₃₂O₄
CFN92779	Zerumin A	176050-48-9	318.5	C₂₀H₃₀O₃
CFN97091	Alepterolic acid	63399-38-2	320.5	C₂₀H₃₂O₃
CFN97090	3-Acetoxy-8(17),13E-labdadien-15-oic acid	63399-37-1	362.5	C₂₂H₃₄O₄
CFN89391	ent-3beta,18-Dihydroxylabda-8(17),13E-dien-15-oic acid	99624-39-2	336.46	C₂₀H₃₂O₄
CFN99412	9-Hydroxy-13E-labden-15-oic acid	132915-47-0	322.5	C₂₀H₃₄O₃