Arecaidine hydrochloride | CAS:6018-28-6

Arecaidine hydrochloride

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Description:

Arecaidine hydrochloride may have carcinogenesis.

In vivo:

Biochem J. 1971 May;122(4):503-8.

The metabolic interconversion of arecoline and arecoline 1-oxide in the rat.[Pubmed: 5123883 ]

METHODS AND RESULTS:
1. Tritiation of arecoline hydrochloride by catalytic exchange in aqueous media (done by The Radiochemical Centre) gave Arecaidine hydrochloride of high specific radioactivity; this on treatment with diazomethane gave [(3)H]arecoline, which was oxidized with peroxyacetic acid to [(3)H]arecoline 1-oxide. 2. Arecoline 1-oxide gave arecaidine 1-oxide on acid hydrolysis and 1,2-dihydro-1-methylnicotinic acid methyl ester on thermal decomposition. 3. [(3)H]Arecoline hydrochloride was metabolized in the rat into the (3)H-labelled derivatives of arecoline 1-oxide, arecaidine 1-oxide, arecaidine, N-acetyl-S-(3-carboxy-1-methylpiperid-4-yl)-l-cysteine and an unidentified metabolite; some unchanged arecoline was also excreted.
CONCLUSIONS:
[(3)H]Arecoline 1-oxide gave the same metabolities, but in different amounts. 4. The possible relevance of these findings to betel-nut carcinogenesis is discussed.

Arecaidine hydrochloride Description

Source:
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Arecaidine hydrochloride
Price:
CAS No.:	6018-28-6
Catalog No.:	CFN93357
Molecular Formula:	C₇H₁₂ClNO₂
Molecular Weight:	177.6 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.6306 mL	28.1532 mL	56.3063 mL	112.6126 mL	140.7658 mL
5 mM	1.1261 mL	5.6306 mL	11.2613 mL	22.5225 mL	28.1532 mL
10 mM	0.5631 mL	2.8153 mL	5.6306 mL	11.2613 mL	14.0766 mL
50 mM	0.1126 mL	0.5631 mL	1.1261 mL	2.2523 mL	2.8153 mL
100 mM	0.0563 mL	0.2815 mL	0.5631 mL	1.1261 mL	1.4077 mL

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CFN98038	Sinapaldehyde	20649-43-8	208.2	C₁₁H₁₂O₄
CFN96414	Ylangenyl acetate	90039-63-7	262.39	C₁₇H₂₆O₂
CFN99071	9-Oxoageraphorone	105181-06-4	234.3	C₁₅H₂₂O₂