Bis-5,5-nortrachelogenin | CAS:870480-56-1

Bis-5,5-nortrachelogenin

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Our products had been exported to the following research institutions and universities, And still growing.

Funda??o Universitária de Dese... (Brazil)
Fraunhofer-Institut für Moleku... (Germany)
Universidade Federal de Pernamb... (Brazil)
University of Vienna (Austria)

University of Padjajaran (Indonesia)
Chulalongkorn University (Thailand)
Uniwersytet Medyczny w ?odzi (Poland)
Complutense University of Madrid (Spain)

University of Bonn (Germany)
Sant Gadge Baba Amravati Univer... (India)
Helmholtz Zentrum München (Germany)
More...

Package

Featured Products

More...

Erigoster B

Catalog No: CFN93294
CAS No: 849777-61-3
Price: $ / mg

Triptolide

Catalog No: CFN99196
CAS No: 38748-32-2
Price: $118/20mg

Pelargonidin-3-O-glucoside chloride

Catalog No: CFN92134
CAS No: 18466-51-8
Price: $490/10mg

Luteolin-4'-O-glucoside

Catalog No: CFN93776
CAS No: 6920-38-3
Price: $ / mg

Ajugol

Catalog No: CFN90759
CAS No: 52949-83-4
Price: $80/20mg

Palmitic acid

Catalog No: CFN99716
CAS No: 57-10-3
Price: $30/20mg

Palmatine hydrochloride

Catalog No: CFN99124
CAS No: 10605-02-4
Price: $30/20mg

Valerenic acid

Catalog No: CFN70254
CAS No: 3569-10-6
Price: $ / mg

Matrine

Catalog No: CFN98835
CAS No: 519-02-8
Price: $30/20mg

11-Oxomogroside III

Catalog No: CFN92192
CAS No: 952481-53-7
Price: $318/10mg

Description:

Bis-5,5-nortrachelogenin has anti-allergic activity, it inhibited NO production with IC50 value of 48.6 microM.

Targets:

In vitro:

Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1348-51.

Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities.[Pubmed: 16205001]

METHODS AND RESULTS:
In our investigation of in vitro anti-allergic screening of medicinal herbal extracts, the ethyl acetate extract of the root of Wikstroemia indica was observed to inhibit nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (IFN-gamma) activated murine macrophage-like cell line, RAW 264.7. Fractionation of the active extract led to the isolation of two new lignan dimer Bis-5,5-nortrachelogenin (1) and bis-5,5'-nortrachelogenin (2), and three known lignans.
CONCLUSIONS:
Compound 1 and lirioresinol B (5) inhibited NO production with IC50 values at 48.6 and 53.5 microM, respectively. Compound 5 also showed free radical scavenging effect on 1,1-diphenyl-2-picrylhydrazil (DPPH) at IC50 values at 19.5 microM.

Bis-5,5-nortrachelogenin Description

Source:	The roots of Wikstroemia indica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Bis-5,5-nortrachelogenin
Price:
CAS No.:	870480-56-1
Catalog No.:	CFN96251
Molecular Formula:	C₄₀H₄₂O₁₄
Molecular Weight:	746.8 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Powder
Source:	The roots of Wikstroemia indica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Lignans Compound Library NO Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.339 mL	6.6952 mL	13.3905 mL	26.7809 mL	33.4762 mL
5 mM	0.2678 mL	1.339 mL	2.6781 mL	5.3562 mL	6.6952 mL
10 mM	0.1339 mL	0.6695 mL	1.339 mL	2.6781 mL	3.3476 mL
50 mM	0.0268 mL	0.1339 mL	0.2678 mL	0.5356 mL	0.6695 mL
100 mM	0.0134 mL	0.067 mL	0.1339 mL	0.2678 mL	0.3348 mL

CFN96234	Isosalicifolin	156974-99-1	356.4	C₂₀H₂₀O₆
CFN98454	Nortrachelogenin	34444-37-6	374.4	C₂₀H₂₂O₇
CFN96714	(+)-Nortrachelogenin	61521-74-2	374.38	C₂₀H₂₂O₇
CFN89300	(7R)-Methoxy-8-epi-matairesinol	198827-23-5	388.41	C₂₁H₂₄O₇
CFN90598	Trachelogenin	34209-69-3	388.15	C₂₁H₂₄O₇
CFN93080	Nortracheloside	33464-78-7	536.53	C₂₆H₃₂O₁₂
CFN90597	Tracheloside	33464-71-0	550.2	C₂₇H₃₄O₁₂
CFN95235	Trachelogenin 4'-O-beta-gentiobioside	106647-13-6	712.7	C₃₃H₄₄O₁₇
CFN95234	Nortrachelogenin-8'-O-beta-glucoside	858127-38-5	536.5	C₂₆H₃₂O₁₂
CFN95251	Nortrachelogenin-5'-C-beta-glucoside	858127-39-6	536.5	C₂₆H₃₂O₁₂