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Caulophylline B
Caulophylline B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Caulophylline B
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CAS No.: 1359978-55-4
Catalog No.: CFN89212
Molecular Formula: C19H21NO5
Molecular Weight: 343.37 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Caulophyllum robustum Maxim.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Caulophylline B is a natural product from Caulophyllum robustum Maxim.
Caulophylline B Description
Source: The roots of Caulophyllum robustum Maxim.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9123 mL 14.5616 mL 29.1231 mL 58.2462 mL 72.8078 mL
5 mM 0.5825 mL 2.9123 mL 5.8246 mL 11.6492 mL 14.5616 mL
10 mM 0.2912 mL 1.4562 mL 2.9123 mL 5.8246 mL 7.2808 mL
50 mM 0.0582 mL 0.2912 mL 0.5825 mL 1.1649 mL 1.4562 mL
100 mM 0.0291 mL 0.1456 mL 0.2912 mL 0.5825 mL 0.7281 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Fitoterapia. 2011 Sep;82(6):793-7.
Four new fluorenone alkaloids and one new dihydroazafluoranthene alkaloid from Caulophyllum robustum Maxim.[Pubmed: 21596111]

METHODS AND RESULTS:
Four new fluorenone alkaloids, caulophylline A, Caulophylline B, caulophylline C,caulophylline D (1-4), and one new dihydroazafluoranthene alkaloid, caulophylline E (5) were isolated from the roots of Caulophyllum robustum Maxim. Their structures were elucidated by spectroscopic analysis.
CONCLUSIONS:
Among the isolated alkaloids, Caulophylline E showed good scavenging effects against DPPH radical with IC(50) of 39 μM.
CFN89212Caulophylline B1359978-55-4343.37C19H21NO5
CFN91984Caulophine1159989-19-1343.37C19H21NO5
CFN91008Atherosperminine5531-98-6309.4C20H23NO2
CFN00068Crassifoline methine133084-00-1343.42C20H25NO4
CFN00085Lavendustin A125697-92-9381.38C21H19NO6
CFN00086Lavendustin B125697-91-8365.38C21H19NO5
CFN00094Tribenzylamine620-40-6288.41C21H21N
CFN00095Trichosanatine169626-16-8444.53C27H28N2O4
CFN901139-Phenylcarbazole1150-62-5243.30C18H13N
CFN901143-Bromo-N-phenylcarbazole1153-85-1322.20C18H12BrN
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