Cinobufotenine | CAS:60657-23-0 | Manufacturer ChemFaces

Cinobufotenine

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $144.7 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Piperine

Catalog No: CFN99919
CAS No: 94-62-2
Price: $30/20mg

Fangchinoline

Catalog No: CFN99167
CAS No: 436-77-1
Price: $40/20mg

6''-O-Malonylgenistin

Catalog No: CFN90631
CAS No: 51011-05-3
Price: $348/5mg

Shikonin

Catalog No: CFN99907
CAS No: 517-88-4
Price: $50/20mg

Cinnamaldehyde

Catalog No: CFN99478
CAS No: 104-55-2
Price: $30/20mg

Pinostrobin

Catalog No: CFN98739
CAS No: 480-37-5
Price: $218/20mg

Arctigenin 4'-O-beta-gentiobioside

Catalog No: CFN90714
CAS No: 41682-24-0
Price: $268/5mg

Senkyunolide A

Catalog No: CFN99594
CAS No: 62006-39-7
Price: $90/20mg

Quercetin-3-O-glucuronide

Catalog No: CFN92172
CAS No: 22688-79-5
Price: $238/20mg

6-Hydroxyrubiadin

Catalog No: CFN97444
CAS No: 87686-86-0
Price: $218/5mg

Description:

Cinobufotenine is a potent stimulant of parasympathetic ganglia and its effect are competitively antagonized by hexamethonium.

In vitro:

Br J Pharmacol. 1980 Aug;69(4):597-600.

A comparison of cinobufotenine (the quaternary derivative of 5-HT) and some related compounds with coryneine (the quaternary derivative of dopamine) on the frog rectus, guinea-pig ileum and rat fundus strip preparations.[Pubmed: 6449223 ]

METHODS AND RESULTS:
1 Coryneine is 2.7 times as active as Cinobufotenine on the frog rectus but on the guinea-pig ileum Cinobufotenine is 1.5 times as active as coryneine. Cinobufotenine is a potent stimulant of parasympathetic ganglia and its effect are competitively antagonized by hexamethonium. 2 The effects of pH on activity relative to a standard whose ionisation is constant (Me4+N or the trimethylammonium analogue of tryptamine) are consistent with the phenate form being weaker than the phenolic form but the changes are smaller than with coryneine because Cinobufotenine is a weaker acid.
CONCLUSIONS:
3 The hydroxyl group makes a large contribution to activity. Cinobufotenine is 9 times as active as the analogue without a hydroxyl on the frog rectus and 12 times as active as it on the ileum. The 5-methoxy analogue is an antagonist on the frog rectus and a very weak partial agonist on the ileum. 4 Cinobufotenine and the quaternary derivative of tryptamine have less than one-thousandth of the activity of 5-hydroxytryptamine on the rat fundus strip.

Cinobufotenine Description

Source:	The glandular body of Bufo bufo gargarizans Cantor.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Cinobufotenine
Price:	$338 / 10mg
CAS No.:	60657-23-0
Catalog No.:	CFN91166
Molecular Formula:	C₁₃H₁₉N₂O
Molecular Weight:	219.3 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The glandular body of Bufo bufo gargarizans Cantor.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.56 mL	22.7998 mL	45.5996 mL	91.1993 mL	113.9991 mL
5 mM	0.912 mL	4.56 mL	9.1199 mL	18.2399 mL	22.7998 mL
10 mM	0.456 mL	2.28 mL	4.56 mL	9.1199 mL	11.3999 mL
50 mM	0.0912 mL	0.456 mL	0.912 mL	1.824 mL	2.28 mL
100 mM	0.0456 mL	0.228 mL	0.456 mL	0.912 mL	1.14 mL

CFN91557	N-Methylserotonin	1134-01-6	190.2	C₁₁H₁₄N₂O
CFN91430	Bufobutanoic acid	74010-65-4	276.3	C₁₄H₁₆N₂O₄
CFN98111	Gramine	87-52-5	174.25	C₁₁H₁₄N₂
CFN91165	Bufotenine	487-93-4	204.3	C₁₂H₁₆N₂O
CFN91166	Cinobufotenine	60657-23-0	219.3	C₁₃H₁₉N₂O
CFN90037	Melatonin	73-31-4	232.28	C₁₃H₁₆N₂O₂
CFN90202	Abrine	526-31-8; 21339-55-9	218.25	C₁₂H₁₄N₂O₂
CFN90634	Hypaphorine	487-58-1	246.3	C₁₄H₁₈N₂O₂
CFN90473	Tryptophan	54-12-6	204.22	C₁₁H₁₂N₂O₂
CFN70337	N-Malonyl DL-tryptophan	3184-74-5	290.3	C₁₄H₁₄N₂O₅