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Coccineone B
Coccineone B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Coccineone B
Price:
CAS No.: 135626-13-0
Catalog No.: CFN96204
Molecular Formula: C16H10O6
Molecular Weight: 298.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The roots of Boerhaavia coccinea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Biological Activity
Description: Reference standards.
Coccineone B Description
Source: The roots of Boerhaavia coccinea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3523 mL 16.7616 mL 33.5233 mL 67.0466 mL 83.8082 mL
5 mM 0.6705 mL 3.3523 mL 6.7047 mL 13.4093 mL 16.7616 mL
10 mM 0.3352 mL 1.6762 mL 3.3523 mL 6.7047 mL 8.3808 mL
50 mM 0.067 mL 0.3352 mL 0.6705 mL 1.3409 mL 1.6762 mL
100 mM 0.0335 mL 0.1676 mL 0.3352 mL 0.6705 mL 0.8381 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Fitoterapia, 2018, 127.
Flavonoids from Mirabilis himalaica.[Reference: WebLink]

METHODS AND RESULTS:
Six previously undescribed flavonoids, 2S-5-methoxy-6-methyl-7,2′-dihydroxyflavanone, 5,7,2′-trihydroxy-6-methylflavone, 5,7,6′-trihydroxy-6-methylcoumaronochromone, 2,4′,6′-trihydroxy-2′-methoxy-3′-methylchalcone, 6R,11-dimethoxy-9-hydroxyrotenoid, and 6R,11-dimethoxy-9-hydroxy-10-methylrotenoid, along with eight known flavonoids, including 2S-5-methoxy-6-methyl-7,4′-dihydroxyflavanone, not previously reported as a natural product, and seven rotenoids, boeravinone A, B, D, P, F, Coccineone B, and mirabijalone E, were isolated from the ethyl acetate soluble fraction of Mirabilis himalaica roots. Their structures were established by the extensive spectroscopic analysis, including HRESIMS, UV, NMR and ECD.
CONCLUSIONS:
All compounds were evaluated for their cytotoxic activities against three human cancer cell lines: A375 (melanoma), A549 (lung), and PLC (hepatoma).
2-Amino-3-carboxy-1,4-naphthoquinone

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CAS No: 173043-38-4
Price: $388/5mg
Sesamolin

Catalog No: CFN99799
CAS No: 526-07-8
Price: $168/20mg
Swertiajaponin

Catalog No: CFN90652
CAS No: 6980-25-2
Price: $218/10mg
Ginsenoside F2

Catalog No: CFN99755
CAS No: 62025-49-4
Price: $40/20mg
Hinokiflavone

Catalog No: CFN92007
CAS No: 19202-36-9
Price: $288/20mg
Kobophenol A

Catalog No: CFN92530
CAS No: 124027-58-3
Price: $318/10mg
Procyanidin B4

Catalog No: CFN91171
CAS No: 29106-51-2
Price: $288/10mg
Lutein

Catalog No: CFN99384
CAS No: 127-40-2
Price: $80/20mg
Parishin A

Catalog No: CFN93112
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Price: $50/20mg
3-Isomangostin

Catalog No: CFN99724
CAS No: 19275-46-8
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