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Coronadiene
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Product Name Coronadiene
Price:
CAS No.: 1145689-64-0
Catalog No.: CFN92778
Molecular Formula: C17H26O2
Molecular Weight: 262.4 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The rhizomes of Curcuma longa L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Standard reference
In vitro:
Chem Pharm Bull (Tokyo). 2008 Dec;56(12):1704-9.
Medicinal flowers. XXIV. Chemical structures and hepatoprotective effects of constituents from flowers of Hedychium coronarium.[Pubmed: 19043243]

METHODS AND RESULTS:
The 80% aqueous acetone extract from the flowers of Hedychium coronarium was found to show a protective effect on D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes. On the other hand, two new labdane-type diterpene glycosides, coronalactosides I (1) and II (2), and a new labdane-type trinorditerpene, Coronadiene (3), were isolated together with 8 known compounds from the extracts, which were obtained with chloroform and 80% aqueous acetone from the flowers of H. coronarium.
CONCLUSIONS:
The structures of new constituents were elucidated on the basis of chemical and physicochemical evidence. In addition, the principal constituents, coronaririn C and 15-hydroxylabda-8(17),11,13-trien-16,15-olide, displayed hepatoprotective effects, which were stronger than that of the hepatoprotective agent, silybin.
Coronadiene Description
Source: The rhizomes of Curcuma longa L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.811 mL 19.0549 mL 38.1098 mL 76.2195 mL 95.2744 mL
5 mM 0.7622 mL 3.811 mL 7.622 mL 15.2439 mL 19.0549 mL
10 mM 0.3811 mL 1.9055 mL 3.811 mL 7.622 mL 9.5274 mL
50 mM 0.0762 mL 0.3811 mL 0.7622 mL 1.5244 mL 1.9055 mL
100 mM 0.0381 mL 0.1905 mL 0.3811 mL 0.7622 mL 0.9527 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Swertiajaponin

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CAS No: 6980-25-2
Price: $218/10mg
Ginsenoside F4

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CAS No: 181225-33-2
Price: $/mg
1,5-Dicaffeoylquinic acid

Catalog No: CFN90937
CAS No: 19870-46-3
Price: $138/20mg
Jionoside A1

Catalog No: CFN90809
CAS No: 120444-60-2
Price: $238/5mg
Senkirkine

Catalog No: CFN00424
CAS No: 2318-18-5
Price: $ /
Cheilanthifoline

Catalog No: CFN90945
CAS No: 483-44-3
Price: $318/10mg
Roemerine

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CAS No: 548-08-3
Price: $318/5mg
Secoisolariciresinol

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Phlorizin

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Liquiritigenin

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Price: $30/20mg
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