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Crotananine
Crotananine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Crotananine
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CAS No.: 71295-28-8
Catalog No.: CFN00366
Molecular Formula: C17H25NO5
Molecular Weight: 323.39 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The seeds of Crotalaria nana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Reference standards.
Crotananine Description
Source: The seeds of Crotalaria nana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0922 mL 15.4612 mL 30.9224 mL 61.8448 mL 77.306 mL
5 mM 0.6184 mL 3.0922 mL 6.1845 mL 12.369 mL 15.4612 mL
10 mM 0.3092 mL 1.5461 mL 3.0922 mL 6.1845 mL 7.7306 mL
50 mM 0.0618 mL 0.3092 mL 0.6184 mL 1.2369 mL 1.5461 mL
100 mM 0.0309 mL 0.1546 mL 0.3092 mL 0.6184 mL 0.7731 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry,1978,17(12):2143-2144.
Novel pyrrolizidine alkaloid from Crotalaria nana[Reference: WebLink]

METHODS AND RESULTS:
Crotananine, isolated from the seeds of Crotalaria nana has been shown by spectroscopy and chemical evidence to be the macrocyclic diester of retronecine and a new C9 necic acid, crotananic acid.
CFN00410Retusamine6883-16-5379.41C19H25NO7
CFN00414Sceleratine6190-25-6369.41C18H27NO7
CFN00471Sceleratine N-oxide103184-92-5385.4C18H27NO8
CFN00423Senecivernine72755-25-0335.40C18H25NO5
CFN00472Senecivernine N-oxide101687-28-9351.4C18H25NO6
CFN00360Cronaburmine71295-32-4323.39C17H25NO5
CFN00366Crotananine71295-28-8323.39C17H25NO5
CFN00372Grantianine633-10-3365.38C18H23NO7
CFN00387Nemorensine50906-96-2337.41C18H27NO5
CFN00406Pterophorine62786-99-6389.40C20H23NO7
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