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Cypellocarpin C
Cypellocarpin C
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Cypellocarpin C
Price:
CAS No.: 294856-66-9
Catalog No.: CFN89273
Molecular Formula: C26H32O11
Molecular Weight: 520.53 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The dried leaves of Eucalyptus cypellocarpa.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Cypellocarpin C shows potent in vitro antitumor-promoting activity, it also can suppress an in vivo two-stage carcinogenesis induced with nitric oxide and TPA on mouse skin.
In vitro:
J Nat Prod. 2000 Sep;63(9):1253-7.
Cypellocarpins A-C, phenol glycosides esterified with oleuropeic acid, from Eucalyptus cypellocarpa.[Pubmed: 11000030]

METHODS AND RESULTS:
Three new phenol glycosides acylated with (+)-oleuropeic acid, cypellocarpin A (1), cypellocarpin B (2), and Cypellocarpin C (3), along with seven known compounds, were isolated from the dried leaves of Eucalyptus cypellocarpa. Structures of the new compounds were determined on the basis of spectroscopic methods, including 2D NMR experiments and chemical degradation.
CONCLUSIONS:
These new compounds and a known related glucoside (7) showed potent in vitro antitumor-promoting activity in a short-term bioassay evaluating the inhibitory effect on Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoyl phorbol 13-acetate (TPA). These compounds also suppressed an in vivo two-stage carcinogenesis induced with nitric oxide and TPA on mouse skin.
Cypellocarpin C Description
Source: The dried leaves of Eucalyptus cypellocarpa.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9211 mL 9.6056 mL 19.2112 mL 38.4224 mL 48.028 mL
5 mM 0.3842 mL 1.9211 mL 3.8422 mL 7.6845 mL 9.6056 mL
10 mM 0.1921 mL 0.9606 mL 1.9211 mL 3.8422 mL 4.8028 mL
50 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7684 mL 0.9606 mL
100 mM 0.0192 mL 0.0961 mL 0.1921 mL 0.3842 mL 0.4803 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2007 Mar;32(6):496-500.
Studies on chemical constituents in fruits of Eucalyptus globulus.[Pubmed: 17552153]
To study the chemical constituents in the fruits of Eucalyptus globulus Labill.
METHODS AND RESULTS:
The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by IR, NMR and MS evidences. Fifteen compounds were obtained and identified as beta-sitosterol (1), betulinic acid (2), stigmasterol (3), euscaphic acid (4), 2a-Hydroxybetulinic acid (5), macrocarpal B (6), macrocarpal A (7), oleanolic acid (8), 3,4,3'-O-trimethylellagic acid (9), 3-O-methylellagic acid 4'-O-(2"-O-acetyl )-alpha-L-rhamnopyranoside (10), camaldulenside (Cypellocarpin C, 11), 3-O-methylellagic acid 4'-O-alpha-L-rhamnopyranoside (12), 3-O-methylellagic acid (13), ellagic acid (14), and gallic acid (15).
CONCLUSIONS:
Compounds 4 and 5 from genera Eucalyptus, 1, 3 and 11 from plant E. globulus, and 6, 7, 9 and 15 from the fruits of E. globulus were isolated for the first time.
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