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Deacetyleupaserrin
Deacetyleupaserrin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Deacetyleupaserrin
Price:
CAS No.: 38456-39-2
Catalog No.: CFN96924
Molecular Formula: C20H26O6
Molecular Weight: 362.42 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The herbs of Eupatorium semiserratum DC.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Biological Activity
Description: Deacetyleupaserrin is an antileukemic sesquiterpene lactone.
Deacetyleupaserrin Description
Source: The herbs of Eupatorium semiserratum DC.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7592 mL 13.7961 mL 27.5923 mL 55.1846 mL 68.9807 mL
5 mM 0.5518 mL 2.7592 mL 5.5185 mL 11.0369 mL 13.7961 mL
10 mM 0.2759 mL 1.3796 mL 2.7592 mL 5.5185 mL 6.8981 mL
50 mM 0.0552 mL 0.2759 mL 0.5518 mL 1.1037 mL 1.3796 mL
100 mM 0.0276 mL 0.138 mL 0.2759 mL 0.5518 mL 0.6898 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Org Chem. 1973 Apr 6;38(7):1260-4.
The isolation and structural elucidation of eupaserrin and deacetyleupaserrin, new antileukemic sesquiterpene lactones from Eupatorium semiserratum[Reference: WebLink]
Evidence is presented for the assignment of structures for eupaserrin (1) and Deacetyleupaserrin (5), two antileukemic sesquiterpene lactones from Eupatorium semiserratum DC.
METHODS AND RESULTS:
Elemental analysis and high resolution mass spectrometry supported a C22H28O7 molecular formula for eupaserrin (1) and a C20H26O6 molecular formula for Deacetyleupaserrin (5). Acetylation of 5 gave 1 and acetyleupaserrin (2), whereas alkaline hydrolysis of 5 gave sarracinic acid. Chemical and spectral evidence indicated the presence of α-methylene-γ-lactone, α,β-unsaturated ester, secondary hydroxyl, and two vinyl methyl groupings in 1 and 5 and suggested that both 1 and 5 were germacranolide dienes. Pyrolysis of 5 gave an oily aldehyde lactone (6), and pyrolysis of 2 gave an enol acetate (3).
CONCLUSIONS:
Chemical and spectral arguments are advanced for assignment of structure and stereochemistry for 2 and 3 and therefore 1 and 5.
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Glycyrrhetinic acid

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CAS No: 471-53-4
Price: $30/20mg
Chebulagic acid

Catalog No: CFN92295
CAS No: 23094-71-5
Price: $ / mg
Atractylenolide III

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CAS No: 73030-71-4
Price: $70/20mg
Cosmosiin

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CAS No: 578-74-5
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Kirenol

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CAS No: 52659-56-0
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Ganoderic acid D

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Myrrhone

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Silymarin

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Price: $30/20mg
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