Deoxynojirimycin hydrochloride | CAS:73285-50-4

Deoxynojirimycin hydrochloride

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Deoxynojirimycin hydrochloride Description

Source:	The root barks of Morus alba L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Kinase Assay:

J. Med. Chem., 2008, 51(19):6188-94.

Chlorogenic acid derivatives with alkyl chains of different lengths and orientations: potent alpha-glucosidase inhibitors.[Pubmed: 18783210]

Alpha-glucosidases play important roles in the digestion of carbohydrates and biosynthesis of viral envelope glycoproteins. Inhibitors of alpha-glucosidase are promising candidates for the development of antitype II diabetics and anti-AIDS drugs.
METHODS AND RESULTS:
Here, we report the synthesis and alpha-glucosidase inhibitory activity of mono- and diketal/acetal derivatives of chlorogenic acid. The diketal derivatives showed more potent inhibitory activity than the monoketals. The 1,7-(5-nonanone) 3,4-(5-nonanone)-chlorogenic acid diketal showed remarkable inhibitory activity against alpha-glucosidases with potency better than that of 1-Deoxynojirimycin hydrochloride. Four diasteremers of pelargonaldehyde diacetal and two of monoacetal derivatives of chlorogenic acid were synthesized in this study.
CONCLUSIONS:
They showed significant potent inhibition similar to or more potent than the ketal counterparts. Acetals with the alkyl chain oriented toward position 2 of chlorogenic acid showed more potent activity than those oriented toward position 6.

Product Name	Deoxynojirimycin hydrochloride
Price:
CAS No.:	73285-50-4
Catalog No.:	CFN90484
Molecular Formula:	C₆H₁₄ClNO₄
Molecular Weight:	199.6 g/mol
Purity:	>=98%
Type of Compound:	Miscellaneous
Physical Desc.:	Powder
Source:	The root barks of Morus alba L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antiviral Compound Library Alpha-glucosidase inhibitors Compound Library Miscellaneous Compound Library

Description:	1-Deoxynojirimycin hydrochloride shows inhibitory activity against α-glucosidases, inhibitors of α-glucosidase are promising candidates for the development of antitype II diabetics and anti-AIDS drugs.
Targets:	α-glucosidase

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.01 mL	25.0501 mL	50.1002 mL	100.2004 mL	125.2505 mL
5 mM	1.002 mL	5.01 mL	10.02 mL	20.0401 mL	25.0501 mL
10 mM	0.501 mL	2.505 mL	5.01 mL	10.02 mL	12.5251 mL
50 mM	0.1002 mL	0.501 mL	1.002 mL	2.004 mL	2.505 mL
100 mM	0.0501 mL	0.2505 mL	0.501 mL	1.002 mL	1.2525 mL

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