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Dihydroxyfumaric acid
Dihydroxyfumaric acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Dihydroxyfumaric acid
Price: $30 / 20mg
CAS No.: 133-38-0
Catalog No.: CFN70059
Molecular Formula: C4H4O6
Molecular Weight: 148.0 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Dihydroxyfumaric acid can induce lipid peroxidation in rat liver microsomes.
In vitro:
Biochemical and Biophysical Research Communications, 1979,89(4):1239-1244.
Dihydroxyfumaric acid induced lipid peroxidation in rat liver microsomes.[Reference: WebLink]
Dihydroxyfumaric acid induced lipid peroxidation in rat liver microsomes.
METHODS AND RESULTS:
This reaction was heat-insensitive contrary to the mitochondrial peroxidation reported in the previous paper, and was enhanced by p-chloromercuribenzoate. Additions of Fe2+ and Fe3+ stimulated both the lipid peroxidation and the disappearance of Dihydroxyfumaric acid. On the other hand, addition of Mn2+ or Cu2+, which stimulated the disappearance of Dihydroxyfumaric acid, inhibited the lipid peroxidation.
CONCLUSIONS:
Hydroxyl radical scavengers, superoxide dismutase and catalase had no effect on this lipid peroxidation and Dihydroxyfumaric acid disappearance. The cytochrome p-450 content decreased about 70 % in parallel with the lipid peroxidation.
Dihydroxyfumaric acid Description
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
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Nature Plants. 2016 Dec 22;3: 16206.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.7568 mL 33.7838 mL 67.5676 mL 135.1351 mL 168.9189 mL
5 mM 1.3514 mL 6.7568 mL 13.5135 mL 27.027 mL 33.7838 mL
10 mM 0.6757 mL 3.3784 mL 6.7568 mL 13.5135 mL 16.8919 mL
50 mM 0.1351 mL 0.6757 mL 1.3514 mL 2.7027 mL 3.3784 mL
100 mM 0.0676 mL 0.3378 mL 0.6757 mL 1.3514 mL 1.6892 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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