Fraxidin | CAS:525-21-3 | Manufacturer ChemFaces

Fraxidin

ChemFaces products have been cited in many studies from excellent and top scientific journals

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $121.9 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Reference standards.

In vitro:

Planta Med. 1999 Oct;65(7):656-8.

In vitro inducible nitric oxide synthesis inhibitory active constituents from Fraxinus rhynchophylla.[Pubmed: 10575381 ]

METHODS AND RESULTS:
Bioassay-guided fractionation of an H2O extract of the barks of Fraxinus rhynchophylla has furnished two inducible nitric oxide synthase (iNOS) inhibitory compounds, ferulaldehyde (1) and scopoletin (3) together with a coumarin, Fraxidin (2).
CONCLUSIONS:
Compounds 1 and 3 showed inhibition of nitric oxide (NO) synthesis in a dose-dependent manner by murine macrophage-like RAW 264.7 cells stimulated with interferon-gamma (IFN-gamma) plus lipopolysaccharide (LPS). The inhibition of NO synthesis of 1 was reflected in the decreased amount of iNOS protein, as determined by Western blotting.

Fraxidin Description

Source:	The herbs of Sarcandra glabra
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Fraxidin
Price:	$268 / 10mg
CAS No.:	525-21-3
Catalog No.:	CFN98860
Molecular Formula:	C₁₁H₁₀O₅
Molecular Weight:	222.2 g/mol
Purity:	>=98%
Type of Compound:	Coumarins
Physical Desc.:	Powder
Source:	The herbs of Sarcandra glabra
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Coumarins Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.5005 mL	22.5023 mL	45.0045 mL	90.009 mL	112.5113 mL
5 mM	0.9001 mL	4.5005 mL	9.0009 mL	18.0018 mL	22.5023 mL
10 mM	0.45 mL	2.2502 mL	4.5005 mL	9.0009 mL	11.2511 mL
50 mM	0.09 mL	0.45 mL	0.9001 mL	1.8002 mL	2.2502 mL
100 mM	0.045 mL	0.225 mL	0.45 mL	0.9001 mL	1.1251 mL

CFN99113	Fraxetin	574-84-5	208.17	C₁₀H₈O₅
CFN99747	Fraxin	524-30-1	370.32	C₁₆H₁₈O₁₀
CFN90181	Isofraxidin	486-21-5	222.19	C₁₁H₁₀O₅
CFN98764	Calycanthoside	483-91-0 (16845-16-2)	384.3	C₁₇H₂₀O₁₀
CFN98860	Fraxidin	525-21-3	222.2	C₁₁H₁₀O₅
CFN97024	6,7,8-Trimethoxycoumarin	6035-49-0	236.2	C₁₂H₁₂O₅
CFN70339	Artemicapin C	334007-19-1	206.2	C₁₀H₆O₅