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Florilenalin
Florilenalin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Florilenalin
Price:
CAS No.: 54964-49-7
Catalog No.: CFN92986
Molecular Formula: C15H20O4
Molecular Weight: 264.32 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The herbs of Helenium amarum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Florilenalin Description
Source: The herbs of Helenium amarum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.7833 mL 18.9165 mL 37.8329 mL 75.6659 mL 94.5823 mL
5 mM 0.7567 mL 3.7833 mL 7.5666 mL 15.1332 mL 18.9165 mL
10 mM 0.3783 mL 1.8916 mL 3.7833 mL 7.5666 mL 9.4582 mL
50 mM 0.0757 mL 0.3783 mL 0.7567 mL 1.5133 mL 1.8916 mL
100 mM 0.0378 mL 0.1892 mL 0.3783 mL 0.7567 mL 0.9458 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journa of Henan Medical University,1997 (1) :89-93.
Relation between electronic structure and anticancerous activity of florilenalin and rabdocalin A[Reference: WebLink]

METHODS AND RESULTS:
MNDO method was used to achieve the quantum chemical calculation of Florilenalin and rabdocalin A.The front molecular orbitals,orbital energies,bond orders,and atomic charges were obtained.
CONCLUSIONS:
The results showed that α methylene β carbonyl 5 numbered ring was an anticancerous zone.The weakest chemical bond was in this zone which consists of the electrophilic πLUMO orbital.Nucleophilic addition took place when the medical molecules approached their target.The other 5,6 or 7 numbered rings had no anticancerous activities.
CFN971744-Epi-isoinuviscolide68832-39-3248.3 C15H20O3
CFN92943Minimolide F1367351-41-4334.41C19H26O5
CFN955098-epi-Confertin110115-60-1248.3C15H20O3
CFN95523Dihydroconfertin68832-40-6250.3C15H22O3
CFN955225-Hydroxy-4a,8-dimethyl-3-methylen-decahydroazuleno[6,5-b]furan-2(3H)-on114579-31-6250.3C15H22O3
CFN993452-Desoxy-4-epi-pulchellin122872-03-1250.3 C15H22O3
CFN99287Carabrolactone B1187925-31-0266.3 C15H22O4
CFN90220Britannin33627-28-0366.41C19H26O7
CFN91552Ergolide54999-07-4306.4C17H22O5
CFN91899Helenalin6754-13-8262.30C15H18O4
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