Structure Identification: |
Chem Pharm Bull (Tokyo). 2001 Apr;49(4):442-6. | Six new dammarane-type triterpene saponins from the leaves of Panax ginseng.[Pubmed: 11310671] | Six new minor saponins, together with known ginsenosides, were isolated from the leaves of Panax ginseng.
METHODS AND RESULTS:
The new saponins were named as ginsenoside Rh5, ginsenoside Rh6, Ginsenoside Rh7, ginsenoside Rh8, ginsenoside Rh9 and ginsenoside Rg7, and their structures were elucidated on the basis of chemical and physicochemical evidence to be as follows: ginsenoside-Rh5: 3beta,6alpha,12beta,24zeta-tetrahydroxy-dammar-20(22),25-diene 6-O-beta-D-glucopyranoside (1), -Rh6: 3beta,6alpha12beta,20(S)-tetrahydroxy-25-hydroperoxy-dammar-23-ene 20-O-beta-D-glucopyranoside (2), -Rh7: 3beta,7beta,12beta,20(S)-tetrahydroxy-dammar-5,24-diene 20-O-beta-D-glucopyranoside (3), -Rh8: 3beta,6alpha,20(S)-trihydroxy-dammar-24-ene-12-one 20-O-beta-D-glucopyranoside (4), -Rh9: 3beta,6alpha,20(S)-trihydroxy-12beta,23-epoxy-dammar-24-ene 20-O-beta-D-glucopyranoside (5) and -Rg7: 3-O-beta-D-glucopyranosyl 3beta,12beta,20(S),24(R)-tetrahydroxy-dammar-25-ene 20-O-beta-D-glucopyranoside (6). |
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