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Grantianine
Grantianine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Grantianine
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CAS No.: 633-10-3
Catalog No.: CFN00372
Molecular Formula: C18H23NO7
Molecular Weight: 365.38 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Crotalaria grantiana
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
Phytochemistry,1984,23(2):473-474.
Grantianine and grantaline, alkaloids of Crotalaria virgulata subsp. Grantiana[Reference: WebLink]

METHODS AND RESULTS:
Characterization data are presented for Grantianine and grantaline, alkaloids of Crotalaria virgulata subsp. grantiana. The plant growing in Australia also contains 1-hydroxymethyl-1β,2β-epoxy-8αH-pyrrolizidine.
Grantianine Description
Source: The herbs of Crotalaria grantiana
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7369 mL 13.6844 mL 27.3688 mL 54.7375 mL 68.4219 mL
5 mM 0.5474 mL 2.7369 mL 5.4738 mL 10.9475 mL 13.6844 mL
10 mM 0.2737 mL 1.3684 mL 2.7369 mL 5.4738 mL 6.8422 mL
50 mM 0.0547 mL 0.2737 mL 0.5474 mL 1.0948 mL 1.3684 mL
100 mM 0.0274 mL 0.1368 mL 0.2737 mL 0.5474 mL 0.6842 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry,1984,23(2):457-459.
Globiferine a pyrrolizidine alkaloid from crotalaria globifera[Reference: WebLink]

METHODS AND RESULTS:
Seeds of Crotalaria globifera from two separate locations in South Africa yielded different pyrrolizidine alkaloids. One batch gave trichodesmine and grantaline, while the other afforded Grantianine and a new pyrrolizidine alkaloid, globiferine.
CFN00472Senecivernine N-oxide101687-28-9351.4C18H25NO6
CFN00360Cronaburmine71295-32-4323.39C17H25NO5
CFN00366Crotananine71295-28-8323.39C17H25NO5
CFN00372Grantianine633-10-3365.38C18H23NO7
CFN00387Nemorensine50906-96-2337.41C18H27NO5
CFN00406Pterophorine62786-99-6389.40C20H23NO7
CFN00410Retusamine6883-16-5379.41C19H25NO7
CFN00414Sceleratine6190-25-6369.41C18H27NO7
CFN00471Sceleratine N-oxide103184-92-5385.4C18H27NO8
CFN00423Senecivernine72755-25-0335.40C18H25NO5
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