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Hydrangetin
Hydrangetin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Hydrangetin
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CAS No.: 485-90-5
Catalog No.: CFN89148
Molecular Formula: C10H8O4
Molecular Weight: 192.17 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The rhizomes of Daphne papyracea var. crassiuscula.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Hydrangetin is a natural product from Daphne papyracea var. crassiuscula.
Hydrangetin Description
Source: The rhizomes of Daphne papyracea var. crassiuscula.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.2037 mL 26.0186 mL 52.0373 mL 104.0745 mL 130.0931 mL
5 mM 1.0407 mL 5.2037 mL 10.4075 mL 20.8149 mL 26.0186 mL
10 mM 0.5204 mL 2.6019 mL 5.2037 mL 10.4075 mL 13.0093 mL
50 mM 0.1041 mL 0.5204 mL 1.0407 mL 2.0815 mL 2.6019 mL
100 mM 0.052 mL 0.2602 mL 0.5204 mL 1.0407 mL 1.3009 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2012 Nov;37(22):3434-7.
Chemical constituents from rhizome of Daphne papyracea var. crassiuscula.[Pubmed: 23373217]
To study chemical constituents from rhizome of Daphne papyracea var. crassiuscula.
METHODS AND RESULTS:
Ethyl acetate fraction of 75% ethanol extracts from rhizome of D. papyracea var. crassiuscula, and its strucutre was identified by spectral method. Nine compounds were separated and identified as daphneticin (1), daphnetin (2), Hydrangetin (3), daphnoretin (4), 1-4'-hydroxyphenyl-5-phenyl-2 (E)-en-1-pentanone (5), daphneolon (6), 3beta-O-acetyl-olean-12-en (7), and (+)-usnic acid (8).
CONCLUSIONS:
Compounds 1-8 were separated from D. papyracea var. crassiuscula for the first time. Compound 8 was separated from the genus for first time.
CFN90807Fabiatrin18309-73-4486.4C21H26O13
CFN99314Scoparone120-08-1206.2 C11H10O4
CFN80132Daphnin486-55-5340.3C15H16O9
CFN90593Daphnetin 7-methyl ether19492-03-6192.17C10H8O4
CFN89148Hydrangetin485-90-5192.17C10H8O4
CFN90594Daphnetin dimethyl ether2445-80-9206.19C11H10O4
CFN930894-Methyldaphnetin2107-77-9192.17C10H8O4
CFN914027-Methoxy-8-hydroxy-4-methylcoumarin22084-94-2206.2C11H10O4
CFN930905,7-Dihydroxy-4-methylcoumarin2107-76-8192.17C10H8O4
CFN991156,7-Dihydroxycoumarin305-01-1178.14C9H6O4
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