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(+)-Isocorynoline
(+)-Isocorynoline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name (+)-Isocorynoline
Price: $138 / 20mg
CAS No.: 475-67-2
Catalog No.: CFN90215
Molecular Formula: C20H23NO4
Molecular Weight: 341.40 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Cryst.
Source: The tubers of Corydalis ambigua
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $28.7 / In-stock
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Targets: Dopamine Receptor | P450 (e.g. CYP17)
(+)-Isocorynoline Description
Source: The tubers of Corydalis ambigua
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9291 mL 14.6456 mL 29.2912 mL 58.5823 mL 73.2279 mL
5 mM 0.5858 mL 2.9291 mL 5.8582 mL 11.7165 mL 14.6456 mL
10 mM 0.2929 mL 1.4646 mL 2.9291 mL 5.8582 mL 7.3228 mL
50 mM 0.0586 mL 0.2929 mL 0.5858 mL 1.1716 mL 1.4646 mL
100 mM 0.0293 mL 0.1465 mL 0.2929 mL 0.5858 mL 0.7323 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron Letters, 1988, 29(50):6621–6623.
A biomimetic synthesis of (±)-corynoline, (±)-11-epicorynoline, (±)-isocorynoline, and (±)-11-epiisocorynoline from corysamine.[Reference: WebLink]

METHODS AND RESULTS:
A novel and efficient synthesis of hexahydrobenzo[c]phenanthridine alkaloids, (±)-corynoline, (±)-11-epicorynoline, (+)-Isocorynoline, (-)-isocorynoline,and (±)-11-epiisocorynoline was accomplished from protoberberine alkaloid, corysamine through a biogenetic route.
CFN99454N-Methyllindcarpine14028-97-8327.4 C19H21NO4
CFN90215(+)-Isocorynoline475-67-2341.40C20H23NO4
CFN90527Corydine476-69-7341.40C20H23NO4
CFN90528Corytuberine517-56-6327.37C19H21NO4
CFN98279Litseglutine B25368-01-8341.4 C20H23NO4
CFN98718Boldine476-70-0327.4 C19H21NO4
CFN98998Cassythicine5890-28-8325.4 C19H19NO4
CFN90408Glaucine475-81-0355.43C21H25NO4
CFN98078Lauroscholtzine2169-44-0341.4 C20H23NO4
CFN89514Nantenine2565-01-7339.38C20H21NO4
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