Isopteleine | CAS:2181-84-2 | Manufacturer ChemFaces

Isopteleine

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Isopteleine shows weak cytotoxic activities against human breast cancer cells (MCF7).

In vitro:

Chin J Nat Med. 2014 Mar;12(3):222-4.

A new quinoline alkaloid from the roots of Dictamnus angustifolius.[Pubmed: 24702810]

To investigate the quinoline alkaloids from the roots of Dictamnus angustifolius G.Don ex Sweet (Rutaceae).
METHODS AND RESULTS:
The quinoline alkaloids were isolated by various column chromatographic methods and their structures were elucidated on the basis of spectral analysis. A new quinoline alkaloid, 5-methoxylrobustine (1), along with five known quinoline alkaloids were obtained, and their structures were identified as dictamnine (2), robustine (3), Isopteleine (4), γ-fagarine (5), and skimmianine (6). Cytotoxicity testing of these alkaloids showed that all of them had weak cytotoxic activities against human breast cancer cells (MCF7).
CONCLUSIONS:
Compound 1 is a new quinoline alkaloid. Alkaloid 3 showed stronger anti-proliferation effect than the other alkaloids.

Isopteleine Description

Source:	The roots of Dictamnus angustifolius G.Don ex Sweet .
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Isopteleine
Price:
CAS No.:	2181-84-2
Catalog No.:	CFN96763
Molecular Formula:	C₁₃H₁₁NO₃
Molecular Weight:	229.23 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The roots of Dictamnus angustifolius G.Don ex Sweet .
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.3624 mL	21.8122 mL	43.6243 mL	87.2486 mL	109.0608 mL
5 mM	0.8725 mL	4.3624 mL	8.7249 mL	17.4497 mL	21.8122 mL
10 mM	0.4362 mL	2.1812 mL	4.3624 mL	8.7249 mL	10.9061 mL
50 mM	0.0872 mL	0.4362 mL	0.8725 mL	1.745 mL	2.1812 mL
100 mM	0.0436 mL	0.2181 mL	0.4362 mL	0.8725 mL	1.0906 mL

CFN90488	Evodine	6989-38-4	329.35	C₁₈H₁₉NO₅
CFN98849	Evoxine	522-11-2	347.4	C₁₈H₂₁NO₆
CFN96762	Isodictamnine	484-74-2	199.20	C₁₂H₉NO₂
CFN96763	Isopteleine	2181-84-2	229.23	C₁₃H₁₁NO₃
CFN96765	Isomaculosidine	518-96-7	259.26	C₁₄H₁₃NO₄
CFN96362	Robustine	2255-50-7	215.2	C₁₂H₉NO₃
CFN98858	gamma-Fagarine	524-15-2	229.2	C₁₃H₁₁NO₃
CFN95126	Maculosidin	522-19-0	259.3	C₁₄H₁₃NO₄
CFN96010	Haplopine	5876-17-5	245.2	C₁₃H₁₁NO₄
CFN92555	Skimmianin	83-95-4	259.3	C₁₄H₁₃NO₄