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Stigmasterol glucoside
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Stigmasterol glucoside
Price: $368 / 5mg
CAS No.: 19716-26-8
Catalog No.: CFN98000
Molecular Formula: C35H58O6
Molecular Weight: 574.8 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The herbs of Perilla frutescens (L.) Britt.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $342.7 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent.
In vitro:
Planta Medica,1985(6):544-545
Plant anticancer agents. XXXVI. Schottenol glucoside from Baccharis coridifolia and Ipomopsis aggregata.[Pubmed: 4095201]
Plant anticancer agents. XXXVI. Schottenol glucoside from Baccharis coridifolia and Ipomopsis aggregata.
In vivo:
Biol Pharm Bull . 2018;41(8):1307-1310.
Screening of Euphorbiaceae Plant Extracts for Anti-5α-reductase[Pubmed: 30068884]
Abstract In our research program to find novel agents for alopecia from natural plant resources, we screened Euphorbiaceae plant extracts using an anti-5α-reductase assay. Among the samples tested, the extract of Phyllanthus urinaria showed the most potent activity with 24.3 and 64.6% inhibition at 50 and 200 μg/mL against the enzyme, respectively. The extract also suppressed the androgen activity of dihydrotestosterone in LNCaP cell line. These results show that the extract of P. urinaria may be a multi-potent agent for androgen-derived alopecia. We tested for activity on a hair regrowth model using mice. The extract of P. urinaria showed hair regrowth activity at 5 mg/mouse/d administration. Furthermore, the active principle for anti-5α-reductase activity was determined as Stigmasterol glucoside from activity-guided fractionation and the IC50 was 27.2 μM. These results suggest that extract of P. urinaria may be a promising candidate anti-alopecia agent. Keywords: 5α-reductase; Euphorbiaceae; Phyllanthus urinaria; androgen receptor; Stigmasterol glucoside.
Stigmasterol glucoside Description
Source: The herbs of Perilla frutescens (L.) Britt.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

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IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
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PMID: 28005066

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7397 mL 8.6987 mL 17.3974 mL 34.7947 mL 43.4934 mL
5 mM 0.3479 mL 1.7397 mL 3.4795 mL 6.9589 mL 8.6987 mL
10 mM 0.174 mL 0.8699 mL 1.7397 mL 3.4795 mL 4.3493 mL
50 mM 0.0348 mL 0.174 mL 0.3479 mL 0.6959 mL 0.8699 mL
100 mM 0.0174 mL 0.087 mL 0.174 mL 0.3479 mL 0.4349 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry. 2008 Feb;69(4):1000-4.
Withanolides from Withania somnifera roots.[Pubmed: 18061221]
Two new and seven known withanolides along with beta-sitosterol, stigmasterol, beta-sitosterol glucoside, Stigmasterol glucoside, alpha+beta glucose were isolated from the roots of Withania somnifera.
METHODS AND RESULTS:
Among the known compounds, Viscosa lactone B, stigmasterol, Stigmasterol glucoside and alpha+beta glucose are being reported from the roots of W. somnifera for the first time. One of the new compounds contained the rare 16beta-acetoxy-17(20)-ene the other contained unusual 6alpha-hydroxy-5,7alpha-epoxy functional groups in the withasteroid skeleton.
CONCLUSIONS:
The structures were elucidated by spectroscopic methods and chemical transformations.
Planta Med.,1973 Mar;23(2):145-8.
Stigmasterol glucoside a constituent of Adenanthera pavonina seed and leaf.[Pubmed: 4705793 ]
Stigmasterol glucoside, dulcitol, a polysaccharide and free stigmasterol from the seeds and octacosanol, dulcitol, glucosides of β–sitosterol and stigmasterol from the leaves have been isolated and characterised. Stigmasterol, Stigmasterol–β–D–glukosid, Dulcitol und ein Polysaccharid aus den Samen und Glukoside von β–Sitosterol und Stigmasterol, Octakosanol und Dulcitol aus den Bl01ttern der Adenanthera pavonina Linn. wurden isoliert und charakterisiert.
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