Lochnericine | CAS:72058-36-7 | Manufacturer ChemFaces

Lochnericine

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Lochnericine Description

Source:	The herbs of Catharanthus roseus (L.)G.Don
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Luminescence. 2015 Mar;30(2):240-6.

Spectroscopy and docking simulations of the interaction between lochnericine and bovine serum albumin.[Pubmed: 24942935]

Lochnericine (LOC) is a component of Voacanga africana, which is a type of traditional medical food in Africa widely used for treating diseases.
METHODS AND RESULTS:
In this article, the interaction between Lochnericine and bovine serum albumin (BSA) was studied by fluorescence spectroscopy. Furthermore, Fourier transform infrared (FTIR), Raman and circular dichroism (CD) were used to investigate the structural changes of BSA. The experimental results consistently indicated that Lochnericine changed the secondary structure of BSA. Three structure-similar components were used to study the interference experiments.
CONCLUSIONS:
The molecular modeling results showed that Lochnericine could bind within not only sites I and II, but also bind the cavity of subdomain IB.

Product Name	Lochnericine
Price:
CAS No.:	72058-36-7
Catalog No.:	CFN97697
Molecular Formula:	C₂₁H₂₄N₂O₃
Molecular Weight:	352.43 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Catharanthus roseus (L.)G.Don
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Dietary supplement Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.8374 mL	14.1872 mL	28.3744 mL	56.7489 mL	70.9361 mL
5 mM	0.5675 mL	2.8374 mL	5.6749 mL	11.3498 mL	14.1872 mL
10 mM	0.2837 mL	1.4187 mL	2.8374 mL	5.6749 mL	7.0936 mL
50 mM	0.0567 mL	0.2837 mL	0.5675 mL	1.135 mL	1.4187 mL
100 mM	0.0284 mL	0.1419 mL	0.2837 mL	0.5675 mL	0.7094 mL

CFN97509	Leuconolam	93710-27-1	326.4	C₁₉H₂₂N₂O₃
CFN97697	Lochnericine	72058-36-7	352.43	C₂₁H₂₄N₂O₃
CFN98678	Tabersonine	4429-63-4	336.4	C₂₁H₂₄N₂O₂
CFN98353	Meloscandonine	28645-27-4	320.4	C₂₀H₂₀N₂O₂
CFN99304	10-Hydroxyscandine	119188-47-5	366.4	C₂₁H₂₂N₂O₄