3-O-beta-D-Glucopyranosylplatycodigenin | CAS:38337-25-6

3-O-beta-D-Glucopyranosylplatycodigenin

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Description:

3-O-beta-D-Glucopyranosylplatycodigenin may have in vitro anti-proliferative activity against the HSC-T6 cell line.

In vitro:

Molecules. 2012 Dec 13;17(12):14899-907.

Two new oleanane-type triterpenoids from Platycodi Radix and anti-proliferative activity in HSC-T6 cells.[Pubmed: 23519261 ]

METHODS AND RESULTS:
Two new oleanane-type triterpenoids, named platycodonoids A and B (1, 2), together with five known saponins, including platycodin D (3), deapioplatycodin D (4), 3-O-β-D-glucopyranosyl polygalacic acid (5), 3-O-beta-D-Glucopyranosylplatycodigenin (6) and polygalacin D (7), were isolated from the roots of Platycodon grandiflorum. On the basis of spectral data and chemical evidence, the structures of the new compounds were elucidated as 2β,3β,23,24-tetrahydroxy-28-nor-olean-12-en-16-one (1) and 2β,3β,23,24- tetrahydroxy-28-nor-olean-12-en-16-one-3-O-β-D-glucopyranoside (2).
CONCLUSIONS:
Compounds 1-7 were evaluated for their in vitro anti-proliferative activity against the HSC-T6 cell line.

3-O-beta-D-Glucopyranosylplatycodigenin Description

Source:	The roots of Platycodon grandiflorum.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Zhongguo Zhong Yao Za Zhi. 2006 Sep;31(18):1506-9.

Chemical constituents from roots of Platycodon grandiflorum.[Pubmed: 17144467]

To study the chemical constituents from roots of Platycodon grandiflorum.
METHODS AND RESULTS:
Column chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data. Eight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-Glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-Glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8).
CONCLUSIONS:
Compounds 1,3 and 5 were isolated from this plant for the first time.

Product Name	3-O-beta-D-Glucopyranosylplatycodigenin
Price:	$268 / 5mg
CAS No.:	38337-25-6
Catalog No.:	CFN90950
Molecular Formula:	C₃₆H₅₈O₁₂
Molecular Weight:	682.85 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The roots of Platycodon grandiflorum.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-proliferation Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.4645 mL	7.3223 mL	14.6445 mL	29.289 mL	36.6113 mL
5 mM	0.2929 mL	1.4645 mL	2.9289 mL	5.8578 mL	7.3223 mL
10 mM	0.1464 mL	0.7322 mL	1.4645 mL	2.9289 mL	3.6611 mL
50 mM	0.0293 mL	0.1464 mL	0.2929 mL	0.5858 mL	0.7322 mL
100 mM	0.0146 mL	0.0732 mL	0.1464 mL	0.2929 mL	0.3661 mL

CFN91588	QS-21	141256-04-4	1990.13	C₉₂H₁₄₈O₄₆
CFN95240	Platycogenin A	1459719-53-9	829.0	C₄₂H₆₈O₁₆
CFN92272	Platycoside M3	917482-69-0	1089.2	C₅₂H₈₀O₂₄
CFN92268	Platyconic acid A	68051-23-0	1239.3	C₅₇H₉₀O₂₉
CFN92354	3''-O-acetyl-platyconic acid A (Platyconic acid B)	1256935-28-0	1281.4	C₅₉H₉₂O₃₀
CFN92353	2''-O-acetyl-platyconic acid A	1256935-30-4	1281.4	C₅₉H₉₂O₃₀
CFN90950	3-O-beta-D-Glucopyranosylplatycodigenin	38337-25-6	682.85	C₃₆H₅₈O₁₂
CFN92271	Platycoside K	899447-64-4	845.0	C₄₂H₆₈O₁₇
CFN92269	Deapi-platycodin D3	67884-05-3	1255.4	C₅₈H₉₄O₂₉
CFN93272	Platycodin D3	67884-03-1	1387.47	C₆₃H₁₀₂O₃₃