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Mayteine
Mayteine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Mayteine
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CAS No.: 104736-05-2
Catalog No.: CFN92119
Molecular Formula: C43H49NO18
Molecular Weight: 867.9 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The roots barks from Maytenus robusta Reiss.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
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  • Cornell University (USA)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Mayteine may have gastroprotective activity.
In vitro:
J Nat Prod. 2004 Jan;67(1):14-8.
Insecticidal sesquiterpene pyridine alkaloids from Maytenus chiapensis.[Pubmed: 14738378 ]

METHODS AND RESULTS:
The new sesquiterpene pyridine alkaloids chiapenines ES-I (1), ES-II (2), ES-III (3), and ES-IV (4), in addition to the known alkaloids wilfordine (5), alatamine (6), wilforidine (7), alatusinine (8), euonine (9), euonymine (10), ebenifoline E-I (11), forrestine (12), Mayteine (13), and 4-hydroxy-7-epi-chuchuhuanine E-V (14), were isolated from the leaves of Maytenus chiapensis.
CONCLUSIONS:
Their structures were elucidated by 1D and 2D NMR spectroscopy, including homonuclear and heteronuclear correlation (COSY, ROESY, HSQC, and HMBC) experiments. Wilfordine, alatusinine, and euonine exhibited strong antifeedant activity against Spodoptera littoralis.
In vivo:
Nat Prod Commun. 2016 May;11(5):597-9.
Phytochemical Analysis and Gastroprotective Activity of the Root Bark from Maytenus robusta.[Pubmed: 27319126]
The present work evaluated the chemical composition and antiulcerogenic potential of the crude extract, fractions and pure compounds isolated of roots barks from Maytenus robusta Reiss, using different pharmacological models in mice.
METHODS AND RESULTS:
3,12-Dioxofriedelane (1) and 11-hydroxylup-20 (29)-en-3-one (2) were isolated from the n-hexane fraction, and Mayteine (3) and 3,7-dioxofriedelane (4) from the dichloromethane fraction. The crude extract (50, 259, 500 mg/kg), all the fractions (250 mg/kg) and cimetidine (100 mg/kg) significantly reduced the lesion index, total lesion area, and percentage of lesions, in comparison with the control group (p < 0.05), by ethanol and NSAID-induced ulcer models. All the isolated compounds also presented significant pharmacological effects at 30 mg/kg.
CONCLUSIONS:
These results show that the root bark of M. robusta may be a promising source of molecules with applicability in the treatment of gastric disorders.
Mayteine Description
Source: The roots barks from Maytenus robusta Reiss.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.1522 mL 5.761 mL 11.5221 mL 23.0441 mL 28.8052 mL
5 mM 0.2304 mL 1.1522 mL 2.3044 mL 4.6088 mL 5.761 mL
10 mM 0.1152 mL 0.5761 mL 1.1522 mL 2.3044 mL 2.8805 mL
50 mM 0.023 mL 0.1152 mL 0.2304 mL 0.4609 mL 0.5761 mL
100 mM 0.0115 mL 0.0576 mL 0.1152 mL 0.2304 mL 0.2881 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Uridine

Catalog No: CFN97000
CAS No: 58-96-8
Price: $30/20mg
Dehydrotrametenolic acid

Catalog No: CFN90577
CAS No: 29220-16-4
Price: $188/20mg
Orientin

Catalog No: CFN98136
CAS No: 28608-75-5
Price: $70/20mg
Syringic acid

Catalog No: CFN98884
CAS No: 530-57-4
Price: $30/20mg
Stylopine

Catalog No: CFN92812
CAS No: 84-39-9
Price: $ / mg
(+)-Epipinoresinol

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Trigonelline

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Continentalic acid

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