Methyl reserpate | CAS:2901-66-8 | Manufacturer ChemFaces

Methyl reserpate

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Methyl reserpate Description

Source:	The roots of Rauwolfia vomitoria
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Methyl reserpate References Information

Citation [1]

J Neurochem. 1987 Mar;48(3):949-53.

Inhibition of norepinephrine transport and reserpine binding by reserpine derivatives.[Pubmed: 3806108]

Reserpine, a competitive inhibitor of catecholamine transport into adrenal medullary chromaffin vesicles, consists of a trimethoxybenzoyl group esterified to an alkaloid ring system. Reserpine inhibits norepinephrine transport with a Ki of approximately 1 nM and binds to chromaffin-vesicle membranes with a KD of about the same value. Methyl reserpate and reserpinediol, derivatives that incorporate the alkaloid ring system, also competitively inhibit norepinephrine transport into chromaffin vesicles with Ki values of 38 +/- 10 nM and 440 +/- 240 nM, respectively. Similar concentrations inhibit [3H]reserpine binding to chromaffin-vesicle membranes. 3,4,5-Trimethoxybenzyl alcohol and 3,4,5-trimethoxybenzoic acid, derivatives of the other part of the reserpine molecule, do not inhibit either norepinephrine transport or [3H]reserpine binding at concentrations up to 100 microM. Moreover, trimethoxybenzyl alcohol does not potentiate the inhibitory action of Methyl reserpate. Therefore, the amine binding site of the catecholamine transporter appears to bind the alkaloid ring system of reserpine rather than the trimethoxybenzoyl moiety. The more potent inhibitors are more hydrophobic compounds, suggesting that the reserpine binding site is hydrophobic.

Product Name	Methyl reserpate
Price:
CAS No.:	2901-66-8
Catalog No.:	CFN92579
Molecular Formula:	C₂₃H₃₀N₂O₅
Molecular Weight:	414.5 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The roots of Rauwolfia vomitoria
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.4125 mL	12.0627 mL	24.1255 mL	48.2509 mL	60.3136 mL
5 mM	0.4825 mL	2.4125 mL	4.8251 mL	9.6502 mL	12.0627 mL
10 mM	0.2413 mL	1.2063 mL	2.4125 mL	4.8251 mL	6.0314 mL
50 mM	0.0483 mL	0.2413 mL	0.4825 mL	0.965 mL	1.2063 mL
100 mM	0.0241 mL	0.1206 mL	0.2413 mL	0.4825 mL	0.6031 mL

CFN98542	Syrosingopine	84-36-6	666.71	C₃₅H₄₂N₂O₁₁
CFN98762	Isorauhimbine	483-09-0	354.5	C₂₁H₂₆N₂O₃
CFN98921	beta-Yohimbine	549-84-8	354.5	C₂₁H₂₆N₂O₃
CFN99400	alpha-Yohimbine	131-03-3	354.5	C₂₁H₂₆N₂O₃
CFN99511	Yohimbine Hydrochloride	65-19-0	390.91	C₂₁H₂₆N₂O₃ HCL
CFN97173	Sempervirine	6882-99-1	272.4	C₁₉H₁₆N₂
CFN92577	Allo-Yohimbine	522-94-1	354.5	C₂₁H₂₆N₂O₃
CFN92579	Methyl reserpate	2901-66-8	414.5	C₂₃H₃₀N₂O₅
CFN92580	Reserpinine	24815-24-5	634.7	C₃₅H₄₂N₂O₉
CFN92583	Reserpin N-oxide	474-48-6	624.7	C₃₃H₄₀N₂O₁₀