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Methylophiopogonone B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Methylophiopogonone B
Price: $318 / 5mg
CAS No.: 74805-89-3
Catalog No.: CFN80321
Molecular Formula: C19H18O5
Molecular Weight: 326.34 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The roots of Ophiopogon japonicus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $270.3 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Methylophiopogonone B is a natural product from Ophiopogon japonicus.
Methylophiopogonone B Description
Source: The roots of Ophiopogon japonicus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0643 mL 15.3214 mL 30.6429 mL 61.2858 mL 76.6072 mL
5 mM 0.6129 mL 3.0643 mL 6.1286 mL 12.2572 mL 15.3214 mL
10 mM 0.3064 mL 1.5321 mL 3.0643 mL 6.1286 mL 7.6607 mL
50 mM 0.0613 mL 0.3064 mL 0.6129 mL 1.2257 mL 1.5321 mL
100 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.6129 mL 0.7661 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhongguo yao xue za zhi,2005,40(5):337-341.
Studies on the liposoluble components from tuber of Ophiopogon japonicus.[Reference: WebLink]

METHODS AND RESULTS:
The compounds were isolated by column chromatography with silica gel and Sephadex LH-20 and the structures were elucidated by spectras' analysis. Sixteen compounds were obtained as 7 homoisoflavones, 2 anthraquinones, 3 phenolic acids, 2 terpenes and 2 fatty acids. Their structures were identified as methylophiopogonanone A(I), methylophiopogonanone B(II), methylophiopogonone A(III), Methylophiopogonone B(IV), 2'-hydroxy-methylophiopogonone A(V), 6-aldehycto-isoophiopogo-nanone A(VI), 5,7-dihyelroxy-8-methoxy-6-methyl-3-(2'-hydroxy-4'-methoxybenzyl) chroman-4-one(VII), chrysophenol(VIII), emodin(IX), vanillic acid(X), P-hydroxy benzaldenhyde (XI), P-trans-coumarinic acid(XII), l-borneol-#beta#-D-glucopyranoside (XIII), oleanolia acid(XIV), azelaic acid (XV) and n-tricosanoic acid(XVI).
CONCLUSIONS:
The compound IV, VIII--XII and XIV--XVI were isolated from O. japonicus and the genus Ophiopogon for the first time, respectively. The types of anthraquinone, phenolic acid and triterpene were firstly obtained from the genus.
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