Odoriflavene | CAS:101153-41-7 | Manufacturer ChemFaces

Odoriflavene

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Description:

Odoriflavene has antioxidant activity, and it also shows inhibition effects on the decrease of glutathione level of rat lens induced by UV irradiation. Odoriflavene shows cytotoxic activity against a SH-SY5Y cell line in vitro.

In vitro:

Food Chemistry, 2007, 104(2):715-720.

Antioxidant activities of compounds isolated from Dalbergia odorifera T. Chen and their inhibition effects on the decrease of glutathione level of rat lens induced by UV irradiation.[Reference: WebLink]

METHODS AND RESULTS:
Four compounds were isolated from the root of Dalbergia odorifera T. Chen and identified by chemical and spectroscopic methods as 2′-O-methyl-isoliquiritigenin (1), Odoriflavene (2), 5′-methoxy-vestitol (3) and formononetin (4). Their antioxidant activities were investigated in lard by the oxidative stability instrument; their inhibitory effects on the decrease of glutathione level of rat lens induced by UV irradiation were studied using a rat lens UV-damage model, and their in vitro cytotoxicity was measured on human SH-SY5Y neuroblastoma cells.
CONCLUSIONS:
Results indicated that all four compounds had obvious antioxidant effects, while none of them showed any synergistic effects on butylated hydroxytoluene or α-tocopherol. When FeCl3 (4.0 μM) was added, the antioxidant activities of the four compounds markedly decreased. The inhibitory effects of compounds 1, 2 and 4 on the decrease of glutathione level of rat lens induced by UV irradiation were comparable to that of α-tocopherol.All four compounds showed cytotoxic activity when evaluated against a SH-SY5Y cell line in vitro.

Odoriflavene Description

Source:	The herbs of Millettia dielsiana
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Chem Pharm Bull (Tokyo). 1992 Sep;40(9):2452-7.

Inhibitors of prostaglandin biosynthesis from Dalbergia odorifera.[Pubmed: 1446367]

METHODS AND RESULTS:
The root heartwood of Dalbergia odorifera T. Chen (Leguminosae) is a Chinese medicinal drug (Japanese name koshinko) used for a stagnant blood syndrome (stagnation of disordered blood; Japanese, oketsu). In addition to 10 known compounds, five new phenolic compounds, isomucronustyrene and hydroxyobtustyrene (cinnamylphenols), (+)-isoduartin (isoflavan), Odoriflavene (isoflav-3-ene) and (-)-odoricarpan (pterocarpan) were isolated and their structures were elucidated on the basis of chemical and spectroscopic methods.
CONCLUSIONS:
Of the fifteen compounds isolated, cinnamylphenols, isoflavans, isoflavene and benzoic acid derivative significantly inhibited prostaglandin biosynthesis as well as platelet aggregation induced by arachidonic acid.

Product Name	Odoriflavene
Price:	$413 / 5mg
CAS No.:	101153-41-7
Catalog No.:	CFN91023
Molecular Formula:	C₁₇H₁₆O₅
Molecular Weight:	300.31 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Millettia dielsiana
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.3299 mL	16.6495 mL	33.2989 mL	66.5978 mL	83.2473 mL
5 mM	0.666 mL	3.3299 mL	6.6598 mL	13.3196 mL	16.6495 mL
10 mM	0.333 mL	1.6649 mL	3.3299 mL	6.6598 mL	8.3247 mL
50 mM	0.0666 mL	0.333 mL	0.666 mL	1.332 mL	1.6649 mL
100 mM	0.0333 mL	0.1665 mL	0.333 mL	0.666 mL	0.8325 mL

CFN96483	Dehydroglyasperin C	199331-35-6	354.4	C₂₁H₂₂O₅
CFN95065	Glyasperin C	142474-53-1	356.4	C₂₁H₂₄O₅
CFN96389	Licoricidin	30508-27-1	424.5	C₂₆H₃₂O₅
CFN96372	Licorisoflavan A	129314-37-0	438.6	C₂₇H₃₄O₅
CFN91578	Phenoxodiol	81267-65-4	240.3	C₁₅H₁₂O₃
CFN96183	Demethylvestitol	65332-45-8	258.3	C₁₅H₁₄O₄
CFN98483	Vestitol	35878-41-2	272.3	C₁₆H₁₆O₄
CFN97016	Isosativan	60102-29-6	286.3	C₁₇H₁₈O₄
CFN89475	(-)-Sativan	41743-86-6	286.32	C₁₇H₁₈O₄
CFN96501	Sativan	71831-00-0	286.32	C₁₇H₁₈O₄