(Z)-23-Coumaroylhederagenin | CAS:654678-61-2

(Z)-23-Coumaroylhederagenin

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Description:

(Z)-23-Coumaroylhederagenin shows significant cytotoxicity against two human tumor cell lines, namely, oral epidermoid carcinoma KB and colorectal carcinoma HT29, and the IC(50) value in the range 1.2-3.6 microM.

In vitro:

J Nat Prod. 2004 Jan;67(1):91-3.

Three new oleanane-type triterpenes from Ludwigia octovalvis with cytotoxic activity against two human cancer cell lines.[Pubmed: 14738395 ]

METHODS AND RESULTS:
Three new oleanane-type triterpenes, (23Z)-coumaroylhederagenin ((Z)-23-Coumaroylhederagenin,1), (23E)-coumaroylhederagenin (2), and (3Z)-coumaroylhederagenin (3), together with two known triterpene acids, oleanolic acid and ursolic acid, have been isolated from the whole plant of Ludwigia octovalvis, and their structures have been elucidated by spectroscopic methods.
CONCLUSIONS:
All three new triterpenes showed significant cytotoxicity against two human tumor cell lines, namely, oral epidermoid carcinoma KB and colorectal carcinoma HT29, and gave IC(50) values in the range 1.2-3.6 microM.

(Z)-23-Coumaroylhederagenin Description

Source:	The herbs of Ludwigia octovalvis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	(Z)-23-Coumaroylhederagenin
Price:
CAS No.:	654678-61-2
Catalog No.:	CFN92845
Molecular Formula:	C₃₉H₅₄O₆
Molecular Weight:	618.4 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The herbs of Ludwigia octovalvis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.6171 mL	8.0854 mL	16.1708 mL	32.3415 mL	40.4269 mL
5 mM	0.3234 mL	1.6171 mL	3.2342 mL	6.4683 mL	8.0854 mL
10 mM	0.1617 mL	0.8085 mL	1.6171 mL	3.2342 mL	4.0427 mL
50 mM	0.0323 mL	0.1617 mL	0.3234 mL	0.6468 mL	0.8085 mL
100 mM	0.0162 mL	0.0809 mL	0.1617 mL	0.3234 mL	0.4043 mL

CFN99636	Uncargenin C	152243-70-4	488.7	C₃₀H₄₈O₅
CFN98227	3-Hydroxy-12-oleanene-23,28-dioic acid	226562-47-6	486.7	C₃₀H₄₆O₅
CFN96468	Uncarinic acid E	277751-61-8	618.84	C₃₉H₅₄O₆
CFN98931	Myriceric acid B	55497-79-5	634.9	C₃₉H₅₄O₇
CFN99683	Myriceric acid C	162059-94-1	797.0	C₄₈H₆₀O₁₀
CFN91480	Sumaresinolic acid	559-64-8	472.7	C₃₀H₄₈O₄
CFN99802	Wilforol C	168254-95-3	472.7	C₃₀H₄₈O₄
CFN98695	Hederagenin	465-99-6	472.7	C₃₀H₄₈O₄
CFN91471	Hederagenin methyl ester	17736-04-8	486.7	C₃₁H₅₀O₄
CFN92845	(Z)-23-Coumaroylhederagenin	654678-61-2	618.4	C₃₉H₅₄O₆