Otosenine | CAS:16958-29-5 | Manufacturer ChemFaces

Otosenine

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

D-Otocenine elicites low toxicity, it shows spasmolytic properties .

In vitro:

Journal of Food Composition and Analysis,2015,42: 1–7.

Hepatotoxic pyrrolizidine alkaloids in Emilia sonchifolia from Taiwan[Reference: WebLink]

METHODS AND RESULTS:
Otonecine bases, senkirkine, Otosenine, neosenkirkine, petasitenine, acetylsenkirkine, desacetyldoronine, acetylpetasitenine, and doronine. Quantification of the individual PAs was determined by six-point linear regression curves in the range of 25–400 μg/mL of senkirkine and senecionine.

In vivo:

Farmakologiia I Toksikologiia, 1979, 42(5):509-11.

Spasmolytic properties of pyrrolizidine alkaloids[Pubmed: 488324]

METHODS AND RESULTS:
Acute toxicity, spasmolytic and hypotensive properties of the alkaloids senecionine, d-otocenine and floridanin isolated from Senecio Erraticum L. were studied.
CONCLUSIONS:
D-Otocenine and floridanin elicited low toxicity, while senecionine and d-Otosenine showed spasmolytic and floridanin predominantly hypotensive properties.

Otosenine Description

Source:	The herbs of Senecio aureus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Otosenine
Price:
CAS No.:	16958-29-5
Catalog No.:	CFN00395
Molecular Formula:	C₁₉H₂₇NO₇
Molecular Weight:	381.42 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Senecio aureus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Toxicity Compound Library Anti-spasmodic Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.6218 mL	13.1089 mL	26.2178 mL	52.4356 mL	65.5445 mL
5 mM	0.5244 mL	2.6218 mL	5.2436 mL	10.4871 mL	13.1089 mL
10 mM	0.2622 mL	1.3109 mL	2.6218 mL	5.2436 mL	6.5545 mL
50 mM	0.0524 mL	0.2622 mL	0.5244 mL	1.0487 mL	1.3109 mL
100 mM	0.0262 mL	0.1311 mL	0.2622 mL	0.5244 mL	0.6554 mL

CFN00395	Otosenine	16958-29-5	381.42	C₁₉H₂₇NO₇
CFN00396	Florosenine	16958-30-8	423.46	C₂₁H₂₉NO₈
CFN00401	Petasitenine	60102-37-6	381.42	C₁₉H₂₇NO₇
CFN00402	Neopetasitenine	60409-51-0	423.46	C₂₁H₂₉NO₈
CFN00425	Neoligularidine	90364-91-3	407.46	C₂₁H₂₉NO₇
CFN00426	Neosenkirkine	57194-70-4	365.42	C₁₉H₂₇NO₆
CFN00428	Acetylanonamine	138079-62-6	423.46	C₂₁H₂₉NO₈
CFN00429	Ligularidine	60872-63-1	407.46	C₂₁H₂₉NO₇
CFN00430	Crotaverrine	60827-69-2	365.42	C₁₉H₂₇NO₆
CFN00432	Syneilesine	55652-65-8	383.44	C₁₉H₂₉NO₇