Science | Nature | Cell | View More
Natural Products
Panaxydiol
Panaxydiol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Panaxydiol
Price: $368 / 10 mg
CAS No.: 63910-76-9
Catalog No.: CFN92798
Molecular Formula: C17H24O2
Molecular Weight: 260.4 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Oil
Source: The roots of Panax ginseng C. A. Mey.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $144.7 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Ioannina (Greece)
  • University of Toronto (Canada)
  • University of Brasilia (Brazil)
  • Hamdard University (India)
  • Sanford Burnham Medical Researc... (USA)
  • Seoul National University of Sc... (Korea)
  • Universiti Sains Malaysia (Malaysia)
  • Korea Intitute of Science and T... (Korea)
  • VIT University (India)
  • University of Sao Paulo (Brazil)
  • Biotech R&D Institute (USA)
  • More...
Package
Featured Products
Nonivamide

Catalog No: CFN90179
CAS No: 2444-46-4
Price: $30/20mg
Hinokiflavone

Catalog No: CFN92007
CAS No: 19202-36-9
Price: $288/20mg
Alpinumisoflavone

Catalog No: CFN98440
CAS No: 34086-50-5
Price: $ /
Isoalantolactone

Catalog No: CFN98107
CAS No: 470-17-7
Price: $40/20mg
trans-Caryophyllene

Catalog No: CFN90502
CAS No: 87-44-5
Price: $30/20mg
1,1,1-Kestopentaose

Catalog No: CFN93044
CAS No: 59432-60-9
Price: $100/20mg
Moschamine

Catalog No: CFN94006
CAS No: 68573-23-9
Price: $218/5mg
Orientin

Catalog No: CFN98136
CAS No: 28608-75-5
Price: $70/20mg
6-Hydroxyrubiadin

Catalog No: CFN97444
CAS No: 87686-86-0
Price: $218/5mg
Stevioside

Catalog No: CFN99548
CAS No: 57817-89-7
Price: $40/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Panaxydiol can inhibit rat liver cholesterol acyltransferase (ACAT) with IC50 values of 45 microM.
In vitro:
J Agric Food Chem. 2005 Apr 6;53(7):2518-23.
Polyacetylenes from the Apiaceae vegetables carrot, celery, fennel, parsley, and parsnip and their cytotoxic activities.[Pubmed: 15796588]
A dichloromethane extract of root celery yielded falcarinol, falcarindiol, Panaxydiol, and the new polyacetylene 8-O-methylfalcarindiol.
METHODS AND RESULTS:
The structure of the new compound was established by one- and two-dimensional (1D and 2D) NMR, mass spectrometry, and optical rotation data. Nonpolar extracts of roots and bulbs of carrots, celery, fennel, parsley, and parsnip were investigated for their content of polyacetylenes by high-performance liquid chromatography with diode array detection (HPLC-DAD). All five species contained polyacetylenes, although carrots and fennel only in minor amounts. Additionally, the cytotoxicity of the four polyacetylenes against five different cell lines was evaluated by the annexin V-PI assay.
CONCLUSIONS:
Falcarinol proved to be the most active compound with a pronounced toxicity against acute lymphoblastic leukemia cell line CEM-C7H2, with an IC(50) of 3.5 micromol/L. The possible chemopreventive impact of the presented findings is discussed briefly.
Panaxydiol Description
Source: The roots of Panax ginseng C. A. Mey.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Neoorthosiphol A

Catalog No: CFN95447
CAS No: 243448-72-8
Price: $318/10mg
New compound 19

Catalog No: CFN95538
CAS No: N/A
Price: $413/5mg
Picraquassioside B

Catalog No: CFN95378
CAS No: 169312-05-4
Price: $318/10mg
3-Oxo-alpha-ilexanolic acid

Catalog No: CFN95496
CAS No: N/A
Price: $413/5mg
New compound 8

Catalog No: CFN95341
CAS No: N/A
Price: $318/5mg
Quercetin 3-O-beta-D-glucosyl-(1->...

Catalog No: CFN95277
CAS No: 143016-74-4
Price: $238/20mg
4-O-Coumaroylquinic acid

Catalog No: CFN95508
CAS No: 53539-37-0
Price: $318/5mg
Ganoderic acid Df

Catalog No: CFN95514
CAS No: 1352033-73-8
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.8402 mL 19.2012 mL 38.4025 mL 76.8049 mL 96.0061 mL
5 mM 0.768 mL 3.8402 mL 7.6805 mL 15.361 mL 19.2012 mL
10 mM 0.384 mL 1.9201 mL 3.8402 mL 7.6805 mL 9.6006 mL
50 mM 0.0768 mL 0.384 mL 0.768 mL 1.5361 mL 1.9201 mL
100 mM 0.0384 mL 0.192 mL 0.384 mL 0.768 mL 0.9601 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Pharm Bull (Tokyo). 2004 Apr;52(4):418-21.
Synthesis of panax acetylenes: chiral syntheses of acetylpanaxydol, PQ-3 and panaxydiol.[Pubmed: 15056955]

METHODS AND RESULTS:
Acetylpanaxydol (1-Ac), PQ-3 (2) and Panaxydiol (3) and their optical isomers were synthesized from L-(+)-diethyl tartrate. The absolute configurations of 1-Ac, 2 and 3 were determined to be 1-Ac (3R,9R,10S), 2 (9R,10S) and 3 (3R,10S), respectively, by comparisons of their optical rotations and the NMR data of their MTPA esters with those of natural products.
Nonivamide

Catalog No: CFN90179
CAS No: 2444-46-4
Price: $30/20mg
Hinokiflavone

Catalog No: CFN92007
CAS No: 19202-36-9
Price: $288/20mg
Alpinumisoflavone

Catalog No: CFN98440
CAS No: 34086-50-5
Price: $ /
Isoalantolactone

Catalog No: CFN98107
CAS No: 470-17-7
Price: $40/20mg
trans-Caryophyllene

Catalog No: CFN90502
CAS No: 87-44-5
Price: $30/20mg
1,1,1-Kestopentaose

Catalog No: CFN93044
CAS No: 59432-60-9
Price: $100/20mg
Moschamine

Catalog No: CFN94006
CAS No: 68573-23-9
Price: $218/5mg
Orientin

Catalog No: CFN98136
CAS No: 28608-75-5
Price: $70/20mg
6-Hydroxyrubiadin

Catalog No: CFN97444
CAS No: 87686-86-0
Price: $218/5mg
Stevioside

Catalog No: CFN99548
CAS No: 57817-89-7
Price: $40/20mg
Tags: buy Panaxydiol | Panaxydiol supplier | purchase Panaxydiol | Panaxydiol cost | Panaxydiol manufacturer | order Panaxydiol | Panaxydiol distributor