Pilosidine | CAS:229971-57-7 | Manufacturer ChemFaces

Pilosidine

ChemFaces products have been cited in many studies from excellent and top scientific journals

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $413 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Pilosidine Description

Source:	The herbs of Curculigo capitulata
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Animal Research:

Farmaco. 2001 May-Jul;56(5-7):353-6.

Studies on vasoconstrictor activity of Curculigo pilosa extracts and of its isolated compounds.[Pubmed: 11482757]

METHODS AND RESULTS:
The Curculigo pilosa total extract, its butanolic fraction (0.5 microg-100 mg/kg) and the most active in vitro compound structurally similar to adrenaline, Pilosidine (10 ng-l mg/kg), caused a reversible and dose-dependent increase in blood pressure in anaesthetized rat. This hypertensive effect is partially reversed (90%) by the prior administration of phentolamine (1 mg/kg) and abolished by pre-treatment with phentolamine (1 mg/kg) and atenolol (100 microg/kg). Neither tachiphylaxis nor any toxic effects were observed.
CONCLUSIONS:
These experimental findings suggest an interaction between C. pilosa and the peripheral adrenergic system (particularly with alpha1 and beta1 receptors); the structure of the bioactive glucosides could be important in evoking this effect.

Product Name	Pilosidine
Price:	$413 / 5mg
CAS No.:	229971-57-7
Catalog No.:	CFN95110
Molecular Formula:	C₂₃H₂₆O₁₁
Molecular Weight:	478.5 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The herbs of Curculigo capitulata
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.0899 mL	10.4493 mL	20.8986 mL	41.7973 mL	52.2466 mL
5 mM	0.418 mL	2.0899 mL	4.1797 mL	8.3595 mL	10.4493 mL
10 mM	0.209 mL	1.0449 mL	2.0899 mL	4.1797 mL	5.2247 mL
50 mM	0.0418 mL	0.209 mL	0.418 mL	0.8359 mL	1.0449 mL
100 mM	0.0209 mL	0.1045 mL	0.209 mL	0.418 mL	0.5225 mL

CFN95477	Malabaricone A	63335-23-9	326.4	C₂₁H₂₆O₃
CFN95475	Malabaricone C	63335-25-1	358.4	C₂₁H₂₆O₅
CFN95481	Giganteone A	460337-13-7	714.9	C₄₂H₅₀O₁₀
CFN95484	Giganteone C	1071223-56-7	698.9	C₄₂H₅₀O₉
CFN95483	Maingayone B	1071223-57-8	684.9	C₄₂H₅₂O₈
CFN95479	Maingayone	271585-66-1	700.9	C₄₂H₅₂O₉
CFN95809	New compound 40	N/A	710.9	C₄₄H₅₄O₈
CFN95103	Cyclocurcumin	153127-42-5	368.4	C₂₁H₂₀O₆
CFN95857	1,5-Epoxy-3R-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane	182227-93-6	390.4	C₂₁H₂₆O₇
CFN95858	1,5-Epoxy-3S-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane	182369-54-6	364.4	C₂₀H₂₈O₆