Pinoresinol diacetate | CAS:32971-25-8

Pinoresinol diacetate

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Pinoresinol diacetate Description

Source:	The barks of Eucommia ulmoides Oliver
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Kinase Assay:

J. Korean Soc. Appl. Bi., 2014, 57(4):473-9.

Pinoresinol Diglucoside is Screened as a Putative alpha-Glucosidase Inhibiting Compound in Actinidia arguta leaves.[Reference: WebLink]

Actinidia arguta leaves are consumed as a popular food material in Korea and have been reported to exert beneficial effects on humans due to its constituent polyphenolic compounds.
METHODS AND RESULTS:
In this study, the alpha-glucosidase inhibitory compounds in A. arguta were screened and identified through alpha-glucosidase-guided fractionation and metabolomic analysis. The 50% ethanol extracts of A. arguta showed strong inhibitory effect (32.6%), which was comparable to acarbose as a positive control (30.0%). Through multiple steps of fractionation, pinoresinol diglucoside and fertaric acid were identified as the major potent compounds in A. arguta inhibiting alpha-glucosidase activity by liquid chromatography mass spectrometry analysis and metabolomic comparison. Particularly, because pinoresinol and its glycosides have been demonstrated as alpha-glucosidase inhibitory agents, pinoresinol diglucoside was proposed to be a putative key compound for alpha-glucosidase inhibition in A. arguta.
CONCLUSIONS:
This is the first study demonstrating the anti-diabetic effect of a pinoresinol-containing fraction of A. arguta and would be useful for its application as a natural alpha-glucosidase inhibitor.

Product Name	Pinoresinol diacetate
Price:
CAS No.:	32971-25-8
Catalog No.:	CFN98420
Molecular Formula:	C₂₄H₂₆O₈
Molecular Weight:	442.5 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Powder
Source:	The barks of Eucommia ulmoides Oliver
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alpha-glucosidase inhibitors Compound Library Lignans Compound Library

Description:	Pinoresinol diacetate inhibits the enzyme α-glucosidase in vitro and may therefore act as a hypoglycemic agent.
Targets:	α-glucosidase

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.2599 mL	11.2994 mL	22.5989 mL	45.1977 mL	56.4972 mL
5 mM	0.452 mL	2.2599 mL	4.5198 mL	9.0395 mL	11.2994 mL
10 mM	0.226 mL	1.1299 mL	2.2599 mL	4.5198 mL	5.6497 mL
50 mM	0.0452 mL	0.226 mL	0.452 mL	0.904 mL	1.1299 mL
100 mM	0.0226 mL	0.113 mL	0.226 mL	0.452 mL	0.565 mL

CFN96723	Epiyangambin	24192-64-1	446.49	C₂₄H₃₀O₈
CFN98775	Pinoresinol	487-36-5	358.4	C₂₀H₂₂O₆
CFN90879	Pinoresinol dimethyl ether	29106-36-3	386.4	C₂₂H₂₆O₆
CFN96266	Eudesmin	526-06-7	386.4	C₂₂H₂₆O₆
CFN96935	3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan	873867-94-8	400.42	C₂₂H₂₄O₇
CFN98420	Pinoresinol diacetate	32971-25-8	442.5	C₂₄H₂₆O₈
CFN97180	Pinoresinol 4-O-beta-D-glucopyranoside	69251-96-3	520.5	C₂₆H₃₂O₁₁
CFN80044	Epipinoresinol-4-O-beta-D-glucoside	24404-49-7	520.52	C₂₆H₃₂O₁₁
CFN99994	Pinoresinol diglucoside	63902-38-5	682.67	C₃₂H₄₂O₁₆
CFN95356	8-Hydroxypinoresinol-4'-O-beta-D-glucopyranoside	102582-69-4	536.5	C₂₆H₃₂O₁₂