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Prerubialatin
Prerubialatin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Prerubialatin
Price:
CAS No.: 1667718-89-9
Catalog No.: CFN96585
Molecular Formula: C27H20O7
Molecular Weight: 456.45 g/mol
Purity: >=98%
Type of Compound: Quinones
Physical Desc.: Powder
Source: The herbs of Rubia cordifolia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Prerubialatin is a precursor of rubialatins A and B.
Prerubialatin Description
Source: The herbs of Rubia cordifolia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1908 mL 10.9541 mL 21.9082 mL 43.8164 mL 54.7705 mL
5 mM 0.4382 mL 2.1908 mL 4.3816 mL 8.7633 mL 10.9541 mL
10 mM 0.2191 mL 1.0954 mL 2.1908 mL 4.3816 mL 5.4771 mL
50 mM 0.0438 mL 0.2191 mL 0.4382 mL 0.8763 mL 1.0954 mL
100 mM 0.0219 mL 0.1095 mL 0.2191 mL 0.4382 mL 0.5477 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Org Lett. 2015 Mar 20;17(6):1441-4.
Biomimetic syntheses of rubialatins A, B and related congeners.[Pubmed: 25723050]
The first total syntheses of rubialatins A and B, two newly discovered naphthohydroquinone dimers, were achieved with high efficiency and elegancy through rationally designed biomimetic approaches. The tandem ring contraction/Michael addition/aldol reaction followed by oxidation enabled the rapid access of Prerubialatin from readily available precursors, which then diverted into rubialatins A and B via epoxidation and photoinduced skeletal rearrangement, respectively. Moreover, several new rubialatin congeners were also obtained along the synthetic tour, some of which were proved to be authentic natural products.
CFN952692-Methoxy-1,4-naphthoquinone2348-82-5188.2C11H8O3
CFN90444Plumbagin481-42-5188.17C11H8O3
CFN95676Chimaphilin482-70-2186.2C12H10O2
CFN956727-(Hydroxymethyl)-2-methyl-1,4-naphthalenedione145626-36-4202.2C12H10O3
CFN95706New compound 33N/A364.4C18H20O8
CFN91989Droserone478-40-0204.18C11H8O4
CFN93018Aristolindiquinone86533-36-0218.20C12H10O4
CFN974122-Methoxystypandrone85122-21-0260.2 C14H12O5
CFN89245Rubioncolin C132242-52-5442.46C27H22O6
CFN929323,3'-Bilawsone33440-64-1346.29C20H10O6
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