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Prometaphanine
Prometaphanine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Prometaphanine
Price:
CAS No.: 6858-85-1
Catalog No.: CFN97167
Molecular Formula: C20H25NO5
Molecular Weight: 359.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Stephania japonica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Reference standards.
Prometaphanine Description
Source: The roots of Stephania japonica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7824 mL 13.9121 mL 27.8242 mL 55.6483 mL 69.5604 mL
5 mM 0.5565 mL 2.7824 mL 5.5648 mL 11.1297 mL 13.9121 mL
10 mM 0.2782 mL 1.3912 mL 2.7824 mL 5.5648 mL 6.956 mL
50 mM 0.0556 mL 0.2782 mL 0.5565 mL 1.113 mL 1.3912 mL
100 mM 0.0278 mL 0.1391 mL 0.2782 mL 0.5565 mL 0.6956 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Yakugaku zasshi journal of the Pharmaceutical Society of Japan, 1967, 87(4):381-386.
Studies on the alkaloids of menispermaceous plants. 230. Alkaloids of formosan Stephania japonica Miers. Structure of prometaphanine.[Reference: WebLink]

METHODS AND RESULTS:
A new, non-phenolic alkaloid was isolated from a Formosan Stephania japonica MIERS and was named Prometaphanine. From its various chemical degradation and spectral data, the structure of this alkaloid was determined as shown by formula (I), including its absolute configuration.
CFN98856Epistephamiersine52389-15-8389.5 C21H27NO6
CFN99040Periglaucine A1025023-04-4373.4 C20H23NO6
CFN96748Periglaucine B1025023-05-5373.40C20H23NO6
CFN99508Sinomenine115-53-7329.38C19H23NO4
CFN99561Sinomenine HCl6080-33-7365.85C19H23NO4.HCl
CFN95807Sinomenine N-oxide1000026-77-6345.4C19H23NO5
CFN92332Fenfangjine G205533-81-9433.5C22H27NO8
CFN9899316-Oxoprometaphanine58738-31-1373.4 C20H23NO6
CFN97167Prometaphanine6858-85-1359.4 C20H25NO5
CFN97858Prostephanaberrine105608-27-3343.38C19H21NO5
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