Puerol A | CAS:152784-32-2 | Manufacturer ChemFaces

Puerol A

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Description:

Puerol A exhibits potent inhibitory effects on aldose reductase with IC50 values of 6.4 uM. dl-Puerol A has antioxdiant activity, it shows inhibitory effects on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro.

Targets:

Aldose reductase

In vitro:

Oriental Pharmacy and Experimental Medicine,2004,4(3):211-4.

Inhibitory effects of dl-Puerol A in the root of Sophora japonica on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro[Reference: WebLink]

METHODS AND RESULTS:
The inhibitory effect of dl-Puerol A as but-2-enolide isolated from Sophora japonica was investigated on copper ion-induced protein oxidative modification in vitro. It inhibited copper-induced protein oxidative modification. However, its inhibitory effect was a little weaker than that of as an antioxidant.
CONCLUSIONS:
The results demonstrated that dl-Puerol A, one of but-2-enolides, might be of use in the oxidative stress.

Puerol A Description

Source:	The stem barks of Sophora japonica.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Puerol A
Price:
CAS No.:	152784-32-2
Catalog No.:	CFN96269
Molecular Formula:	C₁₇H₁₄O₅
Molecular Weight:	298.3 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The stem barks of Sophora japonica.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antioxidants Compound Library Inhibitors Compound Library Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.3523 mL	16.7616 mL	33.5233 mL	67.0466 mL	83.8082 mL
5 mM	0.6705 mL	3.3523 mL	6.7047 mL	13.4093 mL	16.7616 mL
10 mM	0.3352 mL	1.6762 mL	3.3523 mL	6.7047 mL	8.3808 mL
50 mM	0.067 mL	0.3352 mL	0.6705 mL	1.3409 mL	1.6762 mL
100 mM	0.0335 mL	0.1676 mL	0.3352 mL	0.6705 mL	0.8381 mL

CFN97602	(+)-Puerol B 2''-O-glucoside	868409-19-2	474.46	C₂₄H₂₆O₁₀
CFN95155	Puerol B	112343-17-6	312.3	C₁₈H₁₆O₅
CFN95165	Specioside B	126589-95-5	460.4	C₂₃H₂₄O₁₀
CFN95177	Pueroside A	100692-52-2	606.6	C₂₉H₃₄O₁₄
CFN95156	Pueroside C	112343-16-5	474.5	C₂₄H₂₆O₁₀
CFN95141	Pueroside B	100692-54-4	636.6	C₃₀H₃₆O₁₅
CFN97695	Broussonin B	73731-86-9	258.32	C₁₆H₁₈O₃
CFN97694	Broussonin A	73731-87-0	258.32	C₁₆H₁₈O₃
CFN97690	Broussonin C	76045-49-3	312.41	C₂₀H₂₄O₃
CFN98607	1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane	376362-03-7	326.4	C₂₁H₂₆O₃