Pungiolide A | CAS:130395-54-9 | Manufacturer ChemFaces

Pungiolide A

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Description:

Pungiolide A exhibits moderate cytotoxicities with IC50 values in the range of 0.90-6.84 uM.

In vitro:

Phytochemistry. 2016 Dec;132:115-122.

Cytotoxic dimeric xanthanolides from fruits of Xanthium chinense.[Pubmed: 27772796 ]

Nine dimeric xanthanolides, pungiolides F-N, and five known analogues, pungiolides A-E, were isolated from fruits of Xanthium chinense.
METHODS AND RESULTS:
Their structures were elucidated through spectroscopic and electronic circular dichroism (ECD) analyses. Pungiolide F is a xanthanolide dimer with an acyclic linkage. Five of the dimers, pungiolide H, pungiolide L, Pungiolide A, pungiolide C and pungiolide E, exhibited moderate cytotoxicities with IC50 values in the range of 0.90-6.84 μM using taxol as the positive control, which had, by comparison, IC50 values in the range of 0.00118-0.0675 μM.
CONCLUSIONS:
These findings enrich the structural diversity of dimeric sesquiterpene lactones.

Pungiolide A Description

Source:	The herbs of Xanthium pungens
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Pungiolide A
Price:
CAS No.:	130395-54-9
Catalog No.:	CFN80472
Molecular Formula:	C₃₀H₃₆O₇
Molecular Weight:	508.6 g/mol
Purity:	>=98%
Type of Compound:	Sesquiterpenoids
Physical Desc.:	Powder
Source:	The herbs of Xanthium pungens
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Sesquiterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.9662 mL	9.8309 mL	19.6618 mL	39.3236 mL	49.1545 mL
5 mM	0.3932 mL	1.9662 mL	3.9324 mL	7.8647 mL	9.8309 mL
10 mM	0.1966 mL	0.9831 mL	1.9662 mL	3.9324 mL	4.9155 mL
50 mM	0.0393 mL	0.1966 mL	0.3932 mL	0.7865 mL	0.9831 mL
100 mM	0.0197 mL	0.0983 mL	0.1966 mL	0.3932 mL	0.4915 mL

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CFN95847	Zedoalactone C	864430-46-6	266.3	C₁₅H₂₂O₄
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CFN90220	Britannin	33627-28-0	366.41	C₁₉H₂₆O₇
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