Pyrolin | CAS:95-71-6 | Manufacturer ChemFaces

Pyrolin

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Description:

Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.

Targets:

Antifection

In vitro:

Scientia Agricultura Sinica, 2009,42 (8) :2784-2792.

Inhibitory Effect and Antimicrobial Mechanism of Pyrolin on Monilinia fructicola in Peach[Reference: WebLink]

To explore the antifungal activity and potential mechanism of Pyrolin against Monilinia fructicola.
METHODS AND RESULTS:
Agar plate tests was conducted to test the inhibitory effect in-vitro and in vivo of Pyrolin.And doubling dilution method was used to determine the minimal inhibitory concentration(MIC) and minimal fugicide concentration(MFC).Polyphenol oxidase(PPO),peroxidase(POD) and phenylalanine ammonium-lyase(PAL) activities induced by inoculation with Pyrolin and M.fructicola were studied in peach.The ultrastructure of M.fructicola treated by Pyrolin was observed through scanning electron microscope(SEM) and transmission electron microscope(TEM). Pyrolin displayed strong antifungal activity to M.fructicola and the activity was significantly increased when the applied concentration was higher,the MIC value of 0.032 mg·mL-1 and MFC value of 0.156 mg·mL-1.The activities of PPO,POD and PAL in peach increased significantly when inoculated with Pyrolin and M.fructicola,and maintained at a high level throughout the experiment.The observations with SEM revealed that the hyphae distorted,the adhesions mycelium occurred,the cell wall was rupture,cell surface occurred substance of flocculent agglutination.The observations with TEM showed that the hypha became thinning obviously,the inner structure confused,the hyphal cell was damaged severely.
CONCLUSIONS:
Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.

Pyrolin Description

Source:	The herbs of Pyrola calliantha H. Andr.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Pyrolin
Price:
CAS No.:	95-71-6
Catalog No.:	CFN96593
Molecular Formula:	C₇H₈O₂
Molecular Weight:	124.14 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The herbs of Pyrola calliantha H. Andr.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antibacterial Compound Library Antifungal Compound Library Phenols Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	8.0554 mL	40.2771 mL	80.5542 mL	161.1084 mL	201.3855 mL
5 mM	1.6111 mL	8.0554 mL	16.1108 mL	32.2217 mL	40.2771 mL
10 mM	0.8055 mL	4.0277 mL	8.0554 mL	16.1108 mL	20.1386 mL
50 mM	0.1611 mL	0.8055 mL	1.6111 mL	3.2222 mL	4.0277 mL
100 mM	0.0806 mL	0.4028 mL	0.8055 mL	1.6111 mL	2.0139 mL

CFN97207	Specioside	72514-90-0	508.5	C₂₄H₂₈O₁₂
CFN96799	Norpterosin B	1226892-20-1	204.26	C₁₃H₁₆O₂
CFN90185	Columbianetin	3804-70-4	246.26	C₁₄H₁₄O₄
CFN97840	Demethylmurrayanine	123497-84-7	211.22	C₁₃H₉NO₂