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RA-XI
RA-XI
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name RA-XI
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CAS No.: 143277-27-4
Catalog No.: CFN92606
Molecular Formula: C42H50N6O11
Molecular Weight: 814.9 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Rubia cordifolia
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: RA-XI shows potent antitumor activity against P-388.
RA-XI Description
Source: The roots of Rubia cordifolia
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.2271 mL 6.1357 mL 12.2714 mL 24.5429 mL 30.6786 mL
5 mM 0.2454 mL 1.2271 mL 2.4543 mL 4.9086 mL 6.1357 mL
10 mM 0.1227 mL 0.6136 mL 1.2271 mL 2.4543 mL 3.0679 mL
50 mM 0.0245 mL 0.1227 mL 0.2454 mL 0.4909 mL 0.6136 mL
100 mM 0.0123 mL 0.0614 mL 0.1227 mL 0.2454 mL 0.3068 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Pharm Bull (Tokyo). 1992 May;40(5):1352-4.
New antitumor bicyclic hexapeptides, RA-XI, -XII, -XIII and -XIV from Rubia cordifolia.[Pubmed: 1394660]

METHODS AND RESULTS:
Four new bicyclic hexapeptides, named as RA-XI, -XII, XIII and -XIV were isolated from Rubia cordifolia and showed potent antitumor activities against P-388. The structures were elucidated from spectroscopic and chemical evidences.
CONCLUSIONS:
RA-XII, XIII and -XIV were proved to be unique bicyclic hexapeptidic glucosides.
CFN92604RA VII86229-97-2770.9C41H50N6O9
CFN92605RA-V64725-24-2756.9C40H48N6O9
CFN92606RA-XI143277-27-4814.9C42H50N6O11
CFN97902Enniatin B917-13-5639.8C33H57N3O9
CFN97986Enniatin B119914-20-6653.9C34H59N3O9
CFN91976Methylpheophorbide A5594-30-9606.71C36H38N4O5
CFN98204Cytochalasin D22144-77-0507.6 C30H37NO6
CFN70315Cytochalasin C22144-76-9507.6C30H37NO6
CFN96781Cytochalasin B14930-96-2479.61C29H37NO5
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